OBJECTIVE To review paediatric posterior urethral injuries and the current potential management options; because urethral injury due to pelvic fracture in children is rare and has a low incidence, the management of this type of trauma and its complications remains controversial. METHODS We reviewed previous reports identified by searching the PubMed Medline electronic database for clinically ...

Fibrosis is a disease condition characterized by abnormalities of the extracellular matrix, such as accumulation transforming growth factor β, infiltration myofibroblasts, deposition collagen, and generalized dysregulation collagen maturation. It can severely impair function organs replacing normal tissue with highly collagenized thereby reducing elasticity compliance tissues. Fibrotic diseases...

A 2-month-old boy was diagnosed with febrile urinary tract infection. Voiding cystourethrography showed bulbar and anterior urethral strictures, and endoscopic internal urethrotomy was performed. He developed febrile urinary tract infection again and revealed the recurrence of the anterior urethral stricture. Consequently, endoscopic internal urethrotomy was performed 4 times. Because the anter...

BACKGROUND The management of urethral stricture is a challenge to both the urologists and the patients. Thoughtful and satisfactory preoperative evaluation remains important to achieving good outcome. Retrograde urethrography and Micturating Cystourethrography (RUG/MCUG) have been the gold standard imaging technique in the evaluation of anterior urethral stricture but are not without inherent l...

OBJECTIVE To determine the role of ascending urethrogram in decision making for patients with suspected urethral strictures. METHODS Medical Records were reviewed of male patients presenting with lower urinary tract symptoms who were subjected to ascending urethrogram and selected cases for cystourethroscopy from January 2001 to December 2002. Cystourethroscopy was performed on those patients...

OBJECTIVES We aimed to study the effect of trimetazidine (TMZ) on urethral wound repair. MATERIALS AND METHODS A total of 52 male rats were used; 8 groups were formed: 1-week and 3-week control (C1, C3), sham (S1, S3), oral (OT1, OT3), and intraurethral TMZ (IUT1, IUT3) groups. Serum and urine total antioxidant capacity (TAC), total oxidant capacity (TOC), and 8-hydroxy-deoxy-guanosine (8-OHd...

PURPOSE Precise definition of pelvic fracture location may enable prediction of which subjects are at risk for urethral injury and understanding of the pathophysiological mechanism of injury. We determined the specific anterior pelvic injury locations associated with urethral injury. MATERIALS AND METHODS We completed a retrospective, nested case-control study of 119 male patients evaluated a...

The incidence of urethral injuries in reports from Vietnam indicates a moderate variability. Salvatierra and colleagues reported 14 urethral injuries in 252 urological war injuries for an incidence of 5.6%, whereas Selikowitz reported 25 urethral injuries in 250 urological injuries for an incidence of approximately 10%. (Actually, Selikowitz’s incidence would be higher if he had included anteri...

BACKGROUND To date, the morbidity of urethral stricture disease among American men has not been analyzed using national datasets. We sought to analyze the morbidity of urethral stricture disease by measuring the rates of urinary tract infections and urinary incontinence among men with a diagnosis of urethral stricture. METHODS We analyzed Medicare claims data for 1992, 1995, 1998, and 2001 to...