Nyctanthes arbortristis Linn. is a well documented plant. The present study is done to establish the diuretic activity of the water-soluble portions of the ethanolic extracts of its flowers, barks, seeds and leaves. In toxicity study, the extracts were seen to be safe up to the dose of 2.0 gm/kg. For the estimation of diuretic activity, the parameters studied were total urine volume and urine c...

In a study designed to assess the effects of acute emotional stiess on the carbohydrate and lipid metabolism of patients with diabetes mellitus, stress was induced under hypnosis by having the patient abreact the most unpleasant situation of his life. The effects of this stress on blood glucose levels, plasma free fatty acid levels, urinary glucose excretion and urine volume were determined by ...

To determine and quantify the cause of nocturia in men, we describe and evaluate the relative contribution of two complementary indices of nocturia: the nocturia index (Ni), a measure of nocturnal urine overproduction, and the nocturnal bladder capacity index (NBCi), reflective of nocturnal bladder capacity. The records of 100 consecutive men with lower urinary tract symptoms (LUTS), having und...

This is a method for efficiently extracting a wide variety of drugs from urine for toxicological analysis by gas chromatography/mass spectrometry. Before extraction, the urine sample is acetylated, diluted with an equal volume of water, and saturated with NaCl. This solution is then mixed with an equal volume of dichloromethane/acetone (2:1 by vol). The organic (top) phase is aspirated and evap...

Plasma vasopressin concentrations vary throughout the rat oestrus cycle. In order to determine the relationship of these fluctuations to fluid retention, studies were carried out in cycling female albino rats. The animals were housed in individual metabolism cages under 12 hourlight/12 hour dark regimen, with free access to food and water. Urine samples to determine volume, osmolality and eiecr...

Metabolic profiling of biological samples is increasingly used to obtain more insight into the pathophysiology of diseases. For translational studies, biological samples from animal models are explored; however, the volume of these samples can be a limiting factor for metabolic profiling studies. For instance, only a few microliters of urine is often available from small animals like mice. Henc...

Nocturia is one of the most bothersome of all urologic symptoms, yet even a rudimentary classification does not exist. We herein propose a classification system of nocturia based on a retrospective study. The records of 200 consecutive patients with nocturia were reviewed. Evaluation included history, micturition diary (including day, night, and 24-hr voided volume), postvoid residual urine (PV...

Data from both cross-sectional and longitudinal studies provide compelling evidence that circulating blood volume can be influenced by regular physical activity or inactivity. Expansion or contraction of plasma volume can account for most of the alteration in circulating blood volume during the initial 1 to 2 weeks of changing physical activity patterns; after this time, altered blood volume ma...

Results of renal function tests done on 36 patients on prophylactic lithium treatment are compared with those of 28 age matched individuals, also being treated for affective disorders but exposed only to neuroleptics and/or tricyclic antidepressants. 25% of the lithium treated patients had A.D.H. resistant concentration dysfunction resulting in polyuria and polydypsia. Serum lithium levels had ...

Acute renal failure (ARF) is an abrupt decline in renal function, sufficient to result in the retention of nia'ogenous wastes, that is not immediately reversible by manipulation of extrarenal factors. Acute renal failure is not defined in terms of urine volume, and may be present both in oliguric and non-oliguric states. The obligatory daily osmolar load (urea, uric acid, ammonia, etc.) excrete...