To cite: Johari B, Koshy M, Sidek S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014205814 DESCRIPTION A postmenopausal 68-year-old woman was presented with intermittent left-sided abdominal discomfort. She denied any vaginal bleeding, dysuria, changes in bowel habits or constitutional symptoms. There was no family history of malignancy. The clinical e...

BACKGROUND Tissues fibrosis is caused by ischemia-reperfusion injury (IRI) and results in organ dysfunction. In this study, we aimed to investigate whether fibrosis occurs after uterine ischemia-reperfusion injury, and to investigate the effects of puerarin (Pur) on the fibrosis process in rats. MATERIAL AND METHODS Twenty-four female Wistar rats were randomly divided into three groups (8 in ea...

The present study was designed to determine the effect of the spatial gradient from the cervix to the uterine fundus on the control of local prostaglandin H synthase (PGHS) 2 mRNA expression. We performed total cesarean hysterectomies during the last trimester in 12 pregnant baboons, 7 not in labor and 5 in labor, and examined PGHS2 mRNA expression throughout the uterus. PGHS2 mRNA abundance wa...

Leiomyoma of the uterus is the most common tumor of the female pelvis, arising from the uterine smooth muscle. Its prevalence increases during the reproductive age and is seen in nearly half of the women over the age of 35 [1]. Large myomas with degenerations located towards the adnexa may mimic an ovarian neoplasm and can impose a challenge in its diagnosis. Radiological modalities like ultras...

A cesarean scar pregnancy is a pregnancy located within the uterine muscle after previous cesarean sections. Recent years have shown a significant increase in the rate of CS and an improvement in the ultrasound diagnosis, and therefore a trend towards an increase in the rate of CSP cases has been reported in many countries. We report on a case of CSP diagnosed using ultrasound at 5/6 weeks'gest...

Atypical polypoid adenomyoma (APAM) is a rare polypoid tumor of the uterus composed of atypical endometrial glands surrounded by smooth muscle. A 29-year-old nulligravida, was clinically diagnosed with endocervical myoma and underwent trans-uterine cervical resection with hysteroscope. The histopathological diagnosis of specimens was APAM. Eight months later, she diagnosed recurrent uterine tum...

We have demonstrated that extracellular signal-regulated kinase (ERK) plays an important role in the regulation of uterine artery contraction. The present study tested the hypothesis that ERK regulates thick and thin filament regulatory pathways in the uterine artery. Isometric tension, intracellular free Ca2+ concentration ([Ca2+]i), and 20-kDa myosin light chain (LC20) phosphorylation were me...

INTRODUCTION Malignant change in a leiomyoma or uterine fibroid is termed leiomyosarcoma. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases are reported in the literature. Our patient did not have any history of genital bleeding, which is the usual presentation in uterine sarcoma. We report an original case repo...

Spontaneous complete chorioamniotic membrane separation (CMS) without invasive fetal procedure is extremely rare and associated with adverse perinatal outcomes. A woman with complete CMS which was detected at the 21 weeks' gestation. She did not take any fetal invasive procedures before the diagnosis. At 27 weeks' gestation, an emergency Caesarean section was performed because of fetal distress...

Oxytocin is a synthetically prepared hormone that stimulates contractions of uterine smooth muscle and it is used for induction and augmentation of labor as well as in abortions. Adverse effects reported with oxytocin include reflex tachycardia, hypotension, electrocardiographic changes, increased cardiac output, myocardial infarction, alteration in fetal heart rate, seizures, headache, memory ...