Postmenopausal atrophic vagina (PAV) is the thinning of the walls of the vagina and decreased lugae of the vagina. PAV is caused by decreased estrogen levels in postmenopausal women. However, the harmful effects of hormone replacement therapy (HRT) have resulted in considerable caution in its use. Various estrogen agonist treatment options are available. Vitamin D is influences the regulation o...

Address for Correspondence: Cihat Ünlü, Women’s Health Clinic, Abdi Ipekci Caddesi 2/7, 34357 Nişantaşı, İstanbul, Turkey Phone: +90 212 241 45 45 Fax: +90 212 241 44 08 e.mail: [email protected] ©Copyright 2011 by the Turkish-German Gynecological Education and Research Foundation Available online at www.jtgga.org doi:10.5152/jtgga.2011.57 To maintain a healthy vaginal ecosystem or to restore an...

OBJECTIVE To estimate the economic impact of screening for and treatment of bacterial vaginosis during early pregnancy. STUDY DESIGN Data from a clinical study that aligned two screening and treatment strategies and a no-screening or treatment strategy with three gynecologic practices in Berlin were used in decision tree analysis. Costs applied to the clinical outcomes were determined from st...

Objective. To determine if sexual intercourse reduces absorption of vaginal progesterone gel in women and to determine if progesterone is absorbed by the male during intercourse. Study Design. Prospective, randomized, cross over, controlled study of 20 reproductive-aged women and their male sexual partners randomized to receive vaginal progesterone gel (Crinone 8% gel, Actavis Inc., USA) or pla...

Intra-urethral vaginal tape is a rare complication of tension-free vaginal tape (TVT) procedure. A 41year-old woman with intra-urethral vaginal tape after TVT procedure is presented. The presenting symptoms were urge incontinence and dysparonia. The patient has received anticholinergic drugs and vaginal estrogen, but the symptoms had not been resolved with both this regimen. The diagnosis was m...

BACKGROUND Colonization of the female lower genital tract with Lactobacillus provides protection against STIs and adverse pregnancy outcomes. Growth of genital Lactobacillus is postulated to depend on epithelial cell-produced glycogen. However, the amount of cell-free glycogen in genital fluid available for utilization by Lactobacillus is not known. METHODS Eighty-five genital fluid samples f...

OBJECTIVE In this study, we aimed at evaluation of the efficacy of Hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women. MATERIALS AND METHODS We searched MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials (RCT) to explore trials that assessed the effectiveness of H. perforatum and flaxseed on hot flash, vagina...

We have investigated the capacity of vaginal and uterine epithelia (VE and UE) to reexpress normal morphology and hormone responsiveness following cell culture. VE and UE from adult ovariectomized mice were grown in a collagen gel matrix with serum-free medium for 7-10 days. Proliferation of these cells occurs in the absence of 17 beta-estradiol and is not stimulated by 17 beta-estradiol; the V...