BACKGROUND Accurate diagnosis and management of hearing loss (HL) is based on valid and accurate ear-specific and frequency-specific information. This is especially relevant as non-optimal hearing amplification as part of early hearing detection and intervention programmes may result in further delays in the speech and language development of children with HL. Audiological measures utilised may...

Channel allocation is one of the fundamental issues in designing wireless communications systems due to the fact that it determines how the available bandwidth will be managed over the changeable user demands. The limited channel capacity and the increasing requirements for advanced services such as real time video grant channel allocation strategies a special role. Plethora of channel allocati...

High-frequency oscillations (HFO) have been suggested as biomarkers of epileptic tissues. While visual marking of these short and small oscillations is tedious and time-consuming, automatic HFO detectors have not yet met a large consensus. Even though detectors have been shown to perform well when validated against visual marking, the large number of false detections due to their lack of robust...

In epidemiology, the regression discontinuity design has received increasing attention recently and might be an alternative to randomized controlled trials (RCTs) to evaluate treatment effects. In regression discontinuity, treatment is assigned above a certain threshold of an assignment variable for which the treatment effect is adjusted in the analysis. We performed simulations and a validatio...

The identification of conserved sequence tags (CSTs) through comparative genome analysis may reveal important regulatory elements involved in shaping the spatio-temporal expression of genetic information. It is well known that the most significant fraction of CSTs observed in human-mouse comparisons correspond to protein coding exons, due to their strong evolutionary constraints. As we still do...

Tone languages are often reported to make use of utterancelevel intonation as well as of lexical tone. We test the alternative hypotheses that a) the coexistence of lexical tone and utterance-level intonation in tone languages results in a diminished functional load for intonation, and b) that lexical tone and intonation can coexist in tone languages without undermining each other’s functional ...

AIM The aim of the study was to perform a preliminary validation of the Brazilian version of the Child Perceptions Questionnaire 8-10 (CPQ 8-10). METHODS The sample used to test the measurement equivalence was made up of 59 children from 8 to 10 years of age at the Federal University of Minas Gerais, Brazil. The CPQ 8-10 was administered, and clinical exams were performed by a single examiner...

Obtaining spirometric testing and providing those results to individuals who smoke has been advocated as a motivational tool to improve smoking cessation. However, its effectiveness is not known. We conducted a systematic review to determine if this approach improves rates of smoking cessation. Data sources included MEDLINE (1966 to October 2005), the Cochrane Library, and experts in the field....

The development of register deprivation measurements was motivated by the desire to study the effect that register demand has on code improvement and register allocation strategies. In addition to the obvious application of testing the spill mechanism used by the compiler’s register allocator, the register deprivation strategy can be used to determine the relationship between the number of allo...

The impact of ethnobotanical data from surveys of traditional medicinal uses ofplants can be enhanced through the validation of biomedical knowledge that may be embedded in literature. This study aimed to explore the use of informatics approaches, including natural language processing and terminology resources, for extracting and comparing ethnobotanical leads from biomedical literature indexed...