Database Sharing refers to a local multiprocessor architecture where all processors share a common database at the disk level. Transaction systems running in such an environment intend to support high transaction rates with short response times as well as high availability and modular growth. In order to achieve these goals, Database Sharing (DB-sharing) requires an efficient syn­ chronization ...

Multi-drug resistance is the main cause of treatment failure in cancer patients. How to identify molecules underlying drug resistance from multi-omics data remains a great challenge. Here, we introduce a data biased strategy, ProteinRank, to prioritize drug-resistance associated proteins in cancer cells. First, we identified differentially expressed proteins in Adriamycin and Vincristine resist...

Medium density fiberboard (MDF) is an engineered wood product formed by breaking down selected lignin-cellulosic material residuals into fibers, combining it with wax and a resin binder, and then forming panels by applying high temperature and pressure. Because the raw material in the industrial process is ever-changing, the panel industry requires methods for monitoring the composition of thei...

Purpose: Performing controlled user experiments on small devices in naturalistic mobile settings has always proved to be a difficult undertaking for many Human Factors researchers. Difficulties exist, not least, because mimicking natural small device usage suffers from a lack of unobtrusive data to guide experimental design, and then validate that the experiment is proceeding naturally. Methods...

STRUCTURE-ACTIVITY RELATIONSHIP MODEL FOR ESTROGEN RECEPTOR LIGANDS Huihui Wu November 29,2011 Xenoestrogens are spread throughout the environment affecting our daily lives and may produce potential toxic effects on human health. The purpose of this study was to develop a mechanistically reliable model capable of identifying xenoestrogens. Our hypothesis was that there are identifiable structur...

BACKGROUND Intensity inhomogeneity occurs in many medical images, especially in vessel images. Overcoming the difficulty due to image inhomogeneity is crucial for the segmentation of vessel image. METHODS This paper proposes a localized hybrid level-set method for the segmentation of 3D vessel image. The proposed method integrates both local region information and boundary information for ves...

Lymph node stages (pN stages) are primary contributors to survival heterogeneity of the 7th AJCC staging system for colorectal cancer (CRC), indicating spaces for modifications. To implement the modifications, we selected eligible CRC patients from the Surveillance Epidemiology and End Results (SEER) database as participants in a training (n = 6675) and a test cohort (n = 6760), and verified tu...