Methicillin-resistant Staphylococcus aureus (MRSA) often causes serious infections in hospitals. Vancomycin is widely accepted as the standard therapy for MRSA infection, but its widespread use has resulted generation of vancomycin-resistant S. (VRSA). To reduce potential risk and VRSA emergence aquatic environments, we investigated degradation methicillin vancomycin by cold atmospheric pressur...

background and objectives: methicillin resistant staphylococcus aureus (mrsa) is a major nosocomial pathogen causing significant morbidity and mortality. the aim of this study was to evaluate in vitro activities of different antibiotics against methicillin resistant staphylococcus aureus. materials and method: the study was conducted over a period of one year (january 2009 - december 2009) in t...

Enterococci, a part of normal gut flora, are not particularly pathogenic organisms in humans. For example, they do not cause respiratory tract infections. The most frequent enterococcal infections are urinary tract infections. Despite their lack of pathogenicity, enterococci have emerged as significant nosocomial pathogens in the United States and elsewhere. Enterococci are formidable pathogens...

E. faecium was the first reported VRE species, carrying the vanA gene in Brazil. In spite of this, vancomycin-resistant E. faecalis has become the predominant species in Brazilian hospitals. The aim of this study was to evaluate the genetic relatedness of VREs isolated in a Brazilian teaching hospital eight years apart from its first isolation. We analyzed 38 VRE strains obtained from 81 survei...

OBJECTIVE The objective of the study was to investigate the prevalence of vancomycin-resistant Staphylococcus aureus (VRSA). MATERIALS AND METHODS Three hundred and fifty-six S. aureus isolates from the Imam Khomeini hospital in Tehran, Iran, were evaluated for methicillin and decreased vancomycin susceptibility by the microbroth dilution method. The mecA, vanAand vanB genes were targeted by ...

One hundred methicillin-resistant Staphylococcus aureus (MRSA) strains, isolated between 1983 and 1999, were tested alongside the vancomycin hetero-resistant S. aureus (hVRSA) strain Mu 3, and vancomycin-resistant S. aureus (VRSA) strain Mu 50, for their resistance to vancomycin. This was achieved using the screening method described by Hiramatsu, gradient plates, agar incorporation, standard E...

The increasing incidence of Vancomycin resistant Enterococcci (VRE) infection is of concern because of limited treatment options and increased mortality. Here we report a rare case of Vancomycin resistant Enterococccal neonatal sepsis. A Very low birth weight male neonate with respiratory distress and suspected hyaline membrane disease was admitted to NICU had pulmonary haemorrhagia and suspect...

Polymethylmethacrylate (PMMA) impregnated with antibiotics is widely used in the treatment of osteomyelitis and infected arthroplasties. With the emergence of resistant bacterial strains, linezolid, which is active against gram-positive bacteria and toward which resistance has been scarce, has been suggested as an alternative. In the current in vitro study, the authors sought to determine and c...

We studied vancomycin and daptomycin susceptibility in methicillin-resistant Staphylococcus aureus from patients exposed to vancomycin, glycopeptide-intermediate S. aureus, and S. aureus passaged in vancomycin-containing medium. A correlation between vancomycin and daptomycin heteroresistance was noted in some strains, suggesting that exposure of S. aureus to vancomycin may affect susceptibilit...

BACKGROUNDS Staphylococcus aureus has emerged as a major public health concern because of the occurrence of multi-drug resistant strains. This study aimed at investigating the multi-drug and vancomycin resistance profile of S. aureus from different infection sites in some teaching hospitals in Nigeria. METHODS Swabs were collected from different infection sites from out-patients in three teac...