PURPOSE A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose rate irradiation (>50 Gy/s, "FLASH") potentially mitigates this effect. However, research in this field has been strongly limited by the availability of FLASH irradiators suitable for small animal experiments. We present a simple methodologi...

PURPOSE We discuss our experiences with fractionated stereotactic radiotherapy (FSR) in the treatment of cavernous sinus meningiomas. METHODS AND MATERIALS From 1995 to 2006, we monitored 100 patients diagnosed with cavernous sinus meningiomas; 84 female and 16 male patients were included. The mean patient age was 56 years. The most common symptoms were a reduction in visual acuity (57%), dip...

This study of doses to patients from emitted photoneutrons in a medical linear accelerator (Varian 2100C) was carried out. Dose calculation was performed using Monte Carlo Geant4 code. The model was used to calculate the neutron fluence, as a function of the neutron energy inside the treatment room to estimate the effective dose to patients. The ambient dose equivalent versus field size for pat...

A program has been developed to evaluate the delivered fluence of step-and-shoot segmental and sliding window dynamic multileaf collimator (MLC) fields. To automate these checks, a number of tools have been developed using data available from the dynamic log files that can be created each time a dynamic delivery occurs. Experiments were performed with a Varian 2100EX with a 120 leaf MLC equippe...

The percentage depth dose in the build-up region and the surface dose for the 6-MV photon beam from a Varian Clinac 23EX medical linear accelerator was investigated for square field sizes of 5 × 5, 10 × 10, 15 × 15 and 20 × 20 cm(2)using the EGS4nrc Monte Carlo (MC) simulation package. The depth dose was found to change rapidly in the build-up region, and the percentage surface dose increased p...

Covid-19 merupakan suatu penyakit pneumonia yang menjadi penyebab pandemi tahun 2020. Selama berlangsungnya pandemi, terus mengalami mutasi genetik menghasilkan varian-varian baru dengan fenotip, pola transmisi, dan virulensi beragam. WHO sendiri mengelompokkan varian 3 varian, yaitu Variant of Interest (VoI), Variants under Monitoring (VUM), Concern (VoC) (Susilo et al., 2022). Omicron muatsi ...

introduction in this study, we aimed to assess the medium-term energy stability of a 6mv elekta compacttm linear accelerator. to the best of our knowledge, this is the first published article to evaluate this linear accelerator in terms of energy stability. as well as investigating the stability of the linear accelerator energy over a period of several weeks, the results will be useful for esti...

PURPOSE To evaluate the Mobius second-check dosimetry system by comparing it to ionization-chamber dose measurements collected in the recently released Mobius Verification Phantom™ (MVP). For reference, a comparison of these measurements to dose calculated in the primary treatment planning system (TPS), Varian Eclipse with the AcurosXB dose algorithm, is also provided. Finally, patient dose cal...

background: the aim of this work was to study the output factors for linac using different ionization chambers and build up caps. materials and methods: output factors were measured for open square fields (3 × 3 cm to 40 × 40 cm) defined by collimator jaws for 6 and 15 mv photon beams from a varian clinac 2100c accelerator were measured. the measurements in air were performed using compact cyli...

a time-of-flight mass spectrometer (tof-ms) developed in our laboratory at isfahan university of technology is described here. the tof-ms instrument uses laser as the ionization source which provides an opportunity to investigate the ions formed in laser ablation or desorption. the tof-ms has an ionization chamber containing an accelerator and an ion lens to focus the ions into a one meter line...