OBJECTIVE Histological analysis of random quadriceps muscle biopsy specimens can be used to detect vasculitis in patients with rheumatoid arthritis (RA). This study aimed at determining the immunohistological features in patients with clinical suspicion of rheumatoid vasculitis, but without a transmural infiltrate or fibrinoid necrosis of the vessel wall on routine histology. METHODS Three gr...

Optic neuritis is commonly associated with diseases such as Multiple Sclerosis, infections, taking special drugs, etc. but recently we have observed a patient that presented retro bulbar optic neuritis as a manifestation of antiphospholipid syndrome. A 35 y/o young woman with the history of chickenpox admitted to the Qhaem hospital (Mashhad, Iran) with the c/o progressive pain and blurred visio...

background kawasaki disease (kd) is an acute febrile vasculitis of early childhood and the leading cause of acquired heart disease in children. the most important complication of kd is coronary artery aneurysm that may lead to thrombosis and myocardial infarction, occurring in 25% of untreated cases. fortunately, timely treatment decreases it to 2 - 4%. there is no specific test for the diagnos...

Urticarial vasculitis is an uncommon from of cutaneous vasculitis and is extremely rare to present during childhood, especially in boys. It typically presents with multiple systemic inflammatory manifestations. Skin biopsy is needed to confirm the diagnosis. In this report a 10 years old Saudi boy with prolonged urticarial rash, fever, and arthritis is presented. His skin biopsy was consistent ...

Urticarial vasculitis is characterised by inflamed itching or burning red patches or wheals that resemble urticaria but persist for greater than 24 hours. It is often idiopathic but is sometimes associated with collagen-vascular disease, particularly systemic lupus erythematosus. Treatment options include oral antihistamines, oral corticosteroids, dapsone, colchicine or hydroxychloroquine. We d...