In the past decade we have learned a lot about the pathophysiology of septic shock. A lot of experimental research has been performed in vitro and in vivo, showing that hemofiltration can improve hemodynamics and survival. With modern machines, hemofiltration is becoming a sepsis treatment in patients.

Continuous Hemofiltration in the Perioperative Management for Chronic Hemodialysis Patients Undergoing Coronary Artery Bypass Surgery Shigeyuki Makino, Takane Hiraiwa, Toshihiko Kinoshita and Hideki Fujii (Department of Thoracic Surgery, Anjo Kosei Hospital, Aichi, Japan) Coronary artery bypass surgery was performed in 7 chronic hemodialysis patients. Hemodialysis and extracorporeal ultrafiltra...

BACKGROUND Rhabdomyolysis is a widely recognized yet rare complication in statin use. Rhabdomyolysis might be triggered by the prescription of high doses of statins or by statin accumulation due to interactions with concomitant medication. Muscle cell destruction as evidenced by myoglobin elevation can induce potentially life-threatening acute renal failure. CASE PRESENTATION We report a case...

BACKGROUND Omni® (B. Braun, Germany) is a new-generation, continuous renal replacement therapy (CRRT) machine designed to improve user interface, minimize downtime and optimize renal dose delivery. It was never tested in humans. METHODS We used Omni® to provide CRRT in 10 critically ill patients. We collected therapy data, metabolic parameters and evaluated user's satisfaction with a survey. ...