Limb apraxia was investigated with standardised tests in 14 patients whose CT scan provided evidence of a vascular lesion confined to the left basal ganglia, or the thalamus, or both, and not involving the cortex or adjacent white matter. Five patients were severely impaired in imitating movements and pantomiming object use. Four of them also performed poorly when tested with real objects. In t...

INTRODUCTION Cognitive and behavioral impairments are considered to occur frequently in amyotrophic lateral sclerosis/motor neuron disease (MND). Rarely, apraxia has been reported in MND. Orofacial, or buccofacial, apraxia is characterized by a loss of voluntary control of facial, lingual, pharyngeal and masticatory muscles in the presence of preserved reflexive and automatic functions of the s...

道具使用動作が特異的に障害される病態として 2 つの失行型が知られている。「使用の失行」と「パントマイムの失行」である。「使用の失行」と「パントマイムの失行」は, 道具の使用動作を表出する際の障害である点で共通するが, 前者は道具を把持した状態での動作時にみられる障害, 後者は道具を把持しない, パントマイムでの動作時にみられる障害である。つまりこの つの失行は, 道具を把持する, しないという, 課題遂行時の, 外界の条件の違いによって区別される。パントマイムや, 道具の使用を支える神経機構がそれぞれに存在すると仮定すると, こうした外界の条件の違いが, 神経機構を起動, 調整, 停止する「スイッチ」となっている可能性がある。本稿では道具の使用動作を取り巻く つの失行症状が出現するそれぞれの状況を確認した。

The objective of the present study was to determine in a controlled study the efficacy of strategy training in left hemisphere stroke patients with apraxia. A total of 113 left hemisphere stroke patients with apraxia were randomly assigned to two treatment groups; (1) strategy training integrated into usual occupational therapy and (2) usual occupational therapy only. Assessments took place at ...

A 23-year-old woman had presented initially to a podiatrist complaining of poorly fitting shoes during her adolescence. After extensive neurological review, she was diagnosed with ataxia with oculomotor apraxia type 2. This is a progressive autosomal recessive ataxia associated with cerebellar atrophy, peripheral neuropathy and an elevated serum α-fetoprotein. Within Europe, it is the most freq...