Despite the considerable research that has been devoted to schizophrenia and depression over the last years, the understanding of the biological bases of these disabling disorders is still fragmentary. Adoption-, twin-and family studies, provide clear evidence of strong genetic components to these mental disorders, although multiple loci are likely to be involved. The effect of pharmacological ...

OBJECTIVE To screen for influenza virus neuraminidase inhibition and to provide a reference for the clinical treatment of influenza using traditional Chinese medicines (TCM). In this study, 421 crude extracts (solubilized with petroleum ether, ethanol, ethyl acetate, and aqueous solvents) were obtained from 113 TCM. The medicine extracts were then reacted with oseltamivir, using 2'-(4-methylumb...

Tanner, J. M., Whitehouse, R. H., Hughes, P. C. R., and Vince, F. P. (1971). Archives of Disease in Childhood, 46, 745. Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints. (1) Human growth hormone (HGH) has been given for one whole year or longer to 100...

In this paper, we draw from management and educational literature to discuss the emotional experience of instructors when designing and implementing virtual learning activities. Using models of experiential learning (Kolb, 1984 and Vince, 1998) we analyse how the emotional experience of an instructor when designing and implementing a virtual pedagogic activity can lead to its redesign. From our...

Several in vitro and in situ approaches were used to determine the dominant presystemic activation site for (2)-6-aminocarbovir, (2)-carbocyclic 2*,3*-didehydro-2*,3*-dideoxy-6-deoxy-6-aminoguanosine (6AC) conversion in rats. The in vitro disappearance half-lives (mean 6 S.D.) in the cytosolic fractions obtained from homogenates of the intestine, liver, and intestinal contents were 0.4 6 0.1 (n...

Professor Malcolm Dixon’s eightieth birthday fell on 18 April 1979. On behalf of the Molecular Enzymology Group of the Biochemical Society, Dr. R. N. Perham organized a Colloquium in Cambridge on 6th April to celebrate the event. Many of Professor Dixon’s former colleagues and students attended this, and the excellent dinner at King’s College that followed. The speakers at the Colloquium were F...

∗ James N. Collins, Stanford University, [email protected]. Acknowledgements: Thanks to Emily Sataua and Joey Zodiakal for their time as consultants. Data from these two consultants for this project was collected in 2013. Both consultants self-identify as speakers of American Samoa Samoan. Thanks also to Vince Schwenke-Enoka and Rev. Iakopo Leleimalefaga for additional judgements. Thanks to ...

Local medicinal plants from Madina, Saudi Arabia, are used to cure various diseases. However, some can cause adverse health effects. Five different medicinal plants were collected in the city of Madina: mahareeb (Cymbopogon), sheeh (Artemisia), harjal (Cynanchum argel delile), nabipoot (Equisetum), and kafmariam (Vitex agnus-castus). In total, four toxic elements including Al, Pb, As, and Cd we...

The application of a simple, fast and reliable volumetric microrespirometric method to assess respiration of bivalve larvae is discussed. As a model, C. gigas larvae of various sizes were used. Metabolic activity of veliger larvae was assessed by measuring respiratory rate for use in ecophysiological modelling. As an example of the application of this approach, additional measurements of velige...