Background and objective: Drug craving is considered to be a major problem in addiction treatment. Neuroimaging research has revealed various areas for drug craving, among which two key areas are the dorsolateral prefrontal cortex (DLPFC) and the cerebellum. The DLPFC is involved in different cognitive tasks like the inhibitory control over seductive options harboring the promise of immediate r...

The prefrontal cortex (PFC) receives input from sensory neocortical regions and sends projections to the basal forebrain (BF). The present study tested the possibility that pathways from sensory cortical regions via the PFC-BF and from the BF back to specific sensory cortical areas could modulate sensory responses. Two prefrontal areas that responded to stimulation of the primary somatosensory ...

Electrical stimulation of critical sites within the hypothalamus of cats elicits a well coordinated attack upon a rat.' A cat will attack a rat in preference to other objects2 and the choice of object (in some instances, the experimenter) can be determined by the site stimulated.! Vision is used by the cat in locating its target and, under certain experimental conditions, opening of the mouth p...

Retinal implants have been developed as a promising way to restore partial vision for the blind. The observation and analysis of neural activities can offer valuable insights for successful prosthetic electrical stimulation. Retinal ganglion cell (RGC) activities have been investigated to provide knowledge on the requirements for electrical stimulation, such as threshold current and the effect ...

Abstract There is evidence that high-frequency transcranial random noise stimulation (hf-tRNS) effective in improving behavioural performance several visual tasks. However, so far there has been limited research into the spatial and temporal characteristics of hf-tRNS-induced facilitatory effects. In present study, electroencephalogram (EEG) was used to investigate dynamics cortical activity mo...

Neural processing of dynamic continuous visual input, and cognitive influences thereon, are frequently studied in paradigms employing strictly rhythmic stimulation. However, the temporal structure of natural stimuli is hardly ever fully rhythmic but possesses certain spectral bandwidths (e.g. lip movements in speech, gestures). Examining periodic brain responses elicited by strictly rhythmic st...

Visual localization is based on the complex interplay of bottom-up and top-down processing. Based on previous work, the posterior parietal cortex (PPC) is assumed to play an essential role in this interplay. In this study, we investigated the causal role of the PPC in visual localization. Specifically, our goal was to determine whether modulation of the PPC via transcranial direct current stimu...

transcranial current stimulation (tcs) is a neuromodulation method in which the patient is exposed to a mild electric current (direct or alternating) at 1-2 ma, resulting in an increase or a decrease in the brain excitability. this modi.cation in neural activities can be used as a method for functional human brain mapping with causal inferences. this method might also facilitate the treatments ...

Introduction: Transcranial alternating current stimulation (tACS) is emerging as an interventional tool to modulate different functions of the brain, potentially by interacting with intrinsic ongoing neuronal oscillations. Functionally different intrinsic alpha oscillations are found throughout the cortex. Yet it remains unclear whether tACS is capable of specifically modulating the somatosenso...

We sought to study brain temperature in patients with mitochondrial diseases in different functional states compared with healthy participants. Brain temperature and mitochondrial function were monitored in the visual cortex and the centrum semiovale at rest and during and after visual stimulation in seven individuals with mitochondrial diseases (n=5 with mitochondrial DNA mutations and n=2 wit...