Dermoid cysts are rare developmental teratomatous lesions composed of ectodermally derived stratified squamous epithelium and mesodermally derived skin adnexal structures. Although several theories have been postulated, the pathogenesis of dermoid cysts and teratomatous lesions in general is unclear. Ovary is the most frequent affected organ, but it can occur in the mediastinum retroperitoneum,...

Recurrent episodes of painful papules and nodules, mostly located on the labia minora , have been reported under denominations vulvar sebaceous adenitis (14 published cases) acne (16 cases). The primary aim this study was to delve further into clinical pathological features condition. secondary collect therapeutic data. In retrospective cohort files photographs patients with or nodules inner ma...

Abstract Background Solitary fibrous tumours (SFTs) in the female genital tract are uncommon. Resection of these is controversial because it can cause life-threatening haemorrhage. We report a case vulvar SFT that was excised combined abdominal-sacral approach after preoperative embolisation. Case presentation At another hospital, an inoperable intrapelvic tumour diagnosed 34-year-old woman. Co...

We here report the case of a 25-year old primiparous woman presenting with painless bluish cystic lesion within the interlabial sulcus measuring 1.5 cm (A). Excision was performed under local anesthesia. Histological examination showed papillary projections coated by apocrine cells (B) suggesting the diagnosis of hidradenoma papilliferum (HP). It is a rare benign adnexal tumor, but it is the mo...

Pelvic ultrasonography (US) remains the imaging modality most frequently used to detect and characterize adnexal masses. Although evaluation is often aimed at distinguishing benign from malignant masses, the majority of adnexal masses are benign. About 90% of adnexal masses can be adequately characterized with US alone. In this article, the important US features that should allow one to make a ...

BACKGROUND p53 inactivation due to oncogenic viral proteins or mutations is an important molecular mechanism in carcinogenesis, which has also been demonstrated for vulvar carcinoma. To evaluate p53 changes in vulvar carcinogenesis, we analyzed p53 expression in vulvar carcinoma, vulvar intraepithelial neoplasia (VIN), lichen sclerosus (LS) and squamous cell hyperplasia (SH). PATIENTS AND MET...

Vulvar cancer is uncommon and may be confused with genital condylomata. We report two cases of middle-aged women presenting with exophytic vulvar tumors of the midline for which diagnosis of a vulvar squamous cell carcinoma was confirmed by histopathology. Risk factors, staging, and treatment options are discussed.

Female patient, 42-years-old, complaining of difficulty in urinating and swelling in the vulvar area for one year. Her gynecological examination showed extensive injury in the vulvar region and the biopsy done was inconclusive. The removal of the lesion was conducted. After the procedure, the patient remains free of recurrence for 15 months. This case highlights the need to consider angiomyxoma...

Squamous cell carcinoma of the vulva occurs predominantly in the older age group. Although the incidence rate of vulvar intraepithelial neoplasia is increasing, that of squamous cell carcinoma of the vulva is declining, reflecting earlier detection and more successful treatment. In addition to human papillomavirus infection, cigarette smoking is a putative risk factor for vulvar squamous cell c...