BACKGROUND Cutaneous warts are a common complaint to visit dermatologic clinic and its course is variable, ranging from spontaneous resolution to a chronic condition refractory to treatment. OBJECTIVE To evaluate the efficacy and safety of punch biopsy for cutaneous warts. METHODS Thirty-nine patients who received punch biopsy for warts were reviewed through charts and photos. Among them, 1...

The lifetime risk of human papillomavirus (HPV) infection exceeds 50%. HPV infection causes >550,000 cases of cervical and anogenital cancer worldwide annually. Infection also causes precancerous lesions and genital warts. HPV types 16 and 18 cause approximately 70% of HPV-related cancers, and HPV types 6 and 11 cause approximately 90% of cases of genital warts. A quadrivalent vaccine for HPV t...

The Hippo pathway is crucial for not only normal growth and apoptosis but also cell fate specification during development. What controls Hippo pathway activity during cell fate specification is incompletely understood. In this article, we identify the insulator protein BEAF-32 as a regulator of Hippo pathway activity in Drosophila photoreceptor differentiation. Though morphologically uniform, t...

Papillomavirus DNA has been reported recently in the vapor (smoke plume) derived from warts treated with carbon dioxide laser; this raises concerns for operator safety. We therefore have studied a group of human and bovine warts to define further the potential risk of wart therapy and to test whether a surgical mask could reduce exposure. Half of each wart was treated with carbon dioxide laser ...

I N THE RANDOMIZED, PLACEBO-CONTROLLED TRIAL by de Haen et al that appears in this issue of the ARCHIVES, the application of duct tape is compared with placebo as a treatment for common warts. The investigators recruited 103 children in the Netherlands from primary schools and assessed them for warts. Those with warts were randomized to 1 of 2 groups. One group received duct tape to apply to a ...

OBJECTIVE To compare the effectiveness and cost of self treatment of penile warts with a commercial preparation of podophyllotoxin 0.5% (PDX 0.5%) with podophyllin 0.5% and podophyllin 2.0% sourced from Podophyllum emodii. DESIGN A prospective double blind randomised study. SUBJECTS 315 patients with penile warts attending two departments of genitourinary medicine. MAIN OUTCOME MEASURES A...

A total of 56 cases with warts in which podophyllin treatment was either contraindicated or a failure, were treated with nitrous oxide using a Keymed 500 cryosurgical appliance. Forty-three patients who completed treatment were followed-up for three months. Thirty-seven of these had received applications of podophyllin twice weekly for an average period of three months before cryosurgery. The r...

OBJECTIVE Clinical efficacy and safety of Polyphenon(R) E, a defined green tea extract, in external genital warts. DESIGN Randomized, double-blind, placebo-controlled study for up to 12 weeks with a 12-week treatment-free follow-up. SETTING Twenty-eight hospitals and practices in Germany and Russia. PATIENTS Two hundred forty-two outpatients (125 men, 117 women) with 2 to 30 warts (total ...

Background: Non-genital warts are a very common and benign skin disease caused by low-risk Human Papilloma Virus (HPV) infection. Common warts, flat plantar clinical manifestations of non-genital many different types HPV. Data on the prevalence or incidence in Bali is still limited. Therefore, it important to identify as reference for conducting further studies cases. This research studied inci...