The aqueous-ethanolic extract of the Hibiscus rosasinensis aerial parts (Hr.Cr) was studied for the possible presence of spasmogenic and spasmolytic constituents to rationalize some of its traditional uses in gastrointestinal disorders. Segments of isolated rabbit jejunum and guinea-pig ileum, 2-3 cm long were mounted seprately in Tyrode’s solution and aerated with 95% oxygen in carbon dioxide....

We investigated the release of endothelium-derived relaxing factor (EDRF) in response to serotonin and histamine in the human internal mammary artery and saphenous vein. The arteries and veins were obtained intraoperatively and were suspended in organ chambers to record isometric tension. In mammary arteries, histamine (10(-8) to 3 X 10(-6) M) induced relaxations in rings with (70 +/- 5%, IC50,...

Background/Aims Little research has been done to evaluate the effect of stress in exacerbating the symptoms associated with gastroesophageal reflux (GER). We aimed to investigate the effect of acute stress on esophageal motility and GER parameters in healthy volunteers. Methods A total of 10 (M:F = 8:2, median age 34 years-old) healthy volunteers without any recurrent gastrointestinal symptom...

The purpose of this study was to record the discharge characteristics of tibialis anterior motor units over a range of target forces and to import these data, along with previously reported observations, into a computational model to compare experimental and simulated measures of torque variability during isometric contractions with the dorsiflexor muscles. The discharge characteristics of 44 m...

This study investigated effects of caffeine ingestion (8 mg/kg) on maximum voluntary torque (MVT) and voluntary activation of the quadriceps during isometric, concentric and eccentric contractions. Fourteen subjects ingested caffeine and placebo in a randomized, controlled, counterbalanced, double-blind crossover design. Neuromuscular tests were performed before and 1 h after oral caffeine and ...

In this paper, we study a generalization of z-ideals in the ring C(X) of continuous real valued functions on a completely regular Hausdorff space X. The notion of a weak ideal and naturally a weak z-ideal and a prime weak ideal are introduced and it turns out that they behave such as z-ideals in C(X).

In this paper, the notion of Suzuki type generalized $\mathcal{L}$-contractions is introduced and a new fixed point theorem for such contractions established.