CONTEXT Fragile X premutation conditions are associated with a significant degree of psychopathology and thus are of interest to the psychiatrist. Remarkable advances at the molecular level have enhanced our understanding of fragile X premutation disorders. OBJECTIVE The authors review the genetic, molecular, neuroimaging, and clinical (systemic, neurologic, and psychiatric) manifestations of...

BACKGROUND: Fragile X syndrome is the most common cause of inherited X-linked mental retardation. It is due to a mutation in a gene on X chromosome leading to hyper­ expansion of a trinucleotide repeat sequence. The two most common Fragile sites with clinical significance are FRAXA at Xq27.3 comprising CGG repeat and a more distal FRAXE associated with amplification of a GCC repeat, located at ...

Securing fragile nanostructures against external impact is indispensable for offering sufficiently long lifetime in service to nanoengineering products, especially when coming in contact with other substances. Indeed, this problem still remains a challenging task, which may be resolved with the help of smart materials such as shape memory and self-healing materials. Here, we demonstrate a shape...

OVERVIEW: The introduction of low-k and ultralow-k dielectric films in copper-interconnect structures presents serious challenges in test, assembly, and packaging of advanced devices. Low-k films support higher circuit speeds and enable smaller feature sizes by increasing the insulation capability around copper interconnects, but compared to previous generations of silicon-dioxide dielectric la...

Surrounding neighbor blocks dependent fragile watermark scheme has its disadvantages, which couldn’t successfully distinguish where the image has been tampered. In this paper, we propose a random block dependant fragile image watermark scheme. Two series, one is generated by this block and its prior block, the other is generated by this block itself, are embedded into the LSBs of this image blo...

The year 2001 began with the inauguration of a U.S. President deliberately aiming to shift the use of the military away from the numerous humanitarian and peacekeeping interventions of the 1990s toward responding to and defeating conventional threats from nation-states. The mood was optimistic, with the new U.S. national Security Strategy, recently put in place by the departing Clinton administ...

‡ Barry Saver is the lead/corresponding author and wrote the initial draft. Stephen Martin is listed second as he contributed inspiration and major ideas for the manuscript. Ronald Adler is listed third as he provided substantially greater contributions to the ideas and editing of the manuscript than the remaining authors. The other authors are listed alphabetically as they all made roughly com...

We consider the problem of state-feedback stabilization for multi-channel systems in the differential-game theoretic framework where the class of admissible strategies for the players is induced from a solution set of the individual objective functions that are associated with certain dissipativity inequality properties. In such a framework, we characterize the feedback Nash equilibria over an ...