in this research, white spot syndrome virus (wssv) with 105.4ld50.ml-1 inactivated with gamma irradiation at a dose rate of 14-15 kgy.sec-1 was used as a vaccine. three hundred and sixty shrimp of litopenaeus vannamei, medium body weight (mbw) 1.0±0.17g), were prepared and experimentally exposed. they were distributed among four groups, inclusing vaccinated-virus exposed (t1), vaccinated-nonvir...

BACKGROUND RNA interference (RNAi) is a specific and effective approach for inhibiting viral replication by introducing double-stranded (ds)RNA targeting the viral gene. In this study, we employed a combinatorial approach to interfere multiple gene functions of white spot syndrome virus (WSSV), the most lethal shrimp virus, using a single-batch of dsRNA, so-called "multi-WSSV dsRNA." A co-culti...

Our previous study demonstrated that an integrin β subunit of Chinese shrimp (Fenneropenaeus chinensis) (FcβInt) plays an important role in white spot syndrome virus (WSSV) infection. In the present work, in order to further elucidate the potential role of FcβInt in WSSV infection, the recombinant extracellular domain of β integringene of F. Chinensis (rFcβInt-ER) was expressed in Escherichia c...

White spot syndrome virus (WSSV) is a prevalent and virulent pathogen affecting both wild and cultured penaeid shrimp worldwide. Molecular diagnostic tools have made detection of the virus increasingly accurate. However, these techniques are often not readily available for rapid diagnosis in the field or in shrimp production facilities. Shrimple®, an immunochromatographic detection assay for WS...