As neoplasias renais correspondem ao crescimento exacerbado de células tumorais no interior dos rins, classificadas como benignas ou malignas. Neste estudo será abordado sobre as malignas renais, a qual maior prevalência e são representadas pelo carcinoma o tumor Wilms, com finalidade descrever respeito aspectos anatomopatológicos, disseminando informações para diagnóstico manejo precoce. O é m...

Abdominal lump in a child is common and worrisome clinical presentation which necessitates many radiological hematological investigations for diagnosis. Though differential diagnoses are many, detailed history taking thorough examination can help diagnosing the organ involved before doing investigations. We presenting case of Stage 2 Wilms tumour 5 year old presented with abdominal pallor.

Nephroblastoma (Wilms tumor) is the most common primary malignant renal tumor in children. Rarely, it may present in the adult age group. This is a case report of a diagnosed case of a 29-yearold female presenting with right-sided flank pain and hematuria. Abdominal sonogram revealed a right renal mass measuring 1.55 × 1.88 × 1.62 cm on the lower pole of the right kidney. CT scan showed a 2.1 ×...

Genetic instability is frequent in human cancer. Unscheduled tetraploidization can trigger cell transformation and tumorigenesis. We made a cytogenetic analysis by Giemsa-trypsin banding of a stage I, biphasic Wilms tumor diagnosed in a 10-month-old male. An evident karyotypic heterogeneity was found. Four different subclones of tumor cells were observed, with DNA content varying from diploid t...

Only 4-6% of children with renal tumor show inferior vena caval or right atrial infiltration at presentation. Tumor emboli are even rarer, and so far, sudden death as the presenting symptom has only been described at presentation in Wilms' tumor in eight cases. We report a unique case of Wilms' tumor that presented with small pulmonary emboli and immediately after as that was diagnosed before d...

The background of the study was the need to compare the histopathology data pool of surgical specimens of Nigerian children of the Igbo ethnic group with the published parameters of Wilms tumor (WT). This was studied at a Reference Pathology Laboratory during a period of 30 years. Interesting results included the finding that all the patients presented with abdominal swelling. The peak age was ...

Wilms' tumor, an embryonic renal neoplasm diagnosed primarily in young children, can occur in either a noninheritable (sporadic) or a familial form, with the latter presenting earlier and more often at bilateral sites. Although familial Wilms' tumor is thought to develop through inherited and acquired mutational inactivation of the two alÃ-elesof pre disposing tumor suppressor genes, only a sma...

A 20-month-old female presented with a palpable abdominal mass. Imaging revealed bilateral renal masses and pulmonary nodules. The genetic evaluation identified de novo 540kb X-chromosome deletion involving GPC3, PHF6, HPRT1, highly skewed X-inactivation (100:0). This clinical picture was suggestive of Wilms’ tumor in the setting Simpson-Golabi-Behmel Syndrome.