OBJECTIVES/HYPOTHESIS To study longitudinal prevalence of otitis media with effusion (OME) in children between 7 and 16 years of age by cleft group, and hearing sensitivity across time and across frequencies. STUDY DESIGN Retrospective and longitudinal. METHODS All children with cleft palate born from 1991 to 1993 were included in the study (n = 58). Audiological and otological data were re...

The specific aims of this prospective survey were to determine the accuracy of traditional diagnostic tools, such as pneumatic otoscopy, otomicroscopy, and tympanometry, and evaluate the usefulness of myringotomy as a diagnostic method; also to determine the significance of myringotomy in treating otitis media with effusion (OME). The status of middle ear of 51 children (85 ears) from November ...

Dichotic listening performance was studied in children who at an early age had undergone a myringotomy with insertion of ventilating tubes for persistent middle ear infections (otitis media with effusion; OME) and compared with age-equivalent children who had no history of otitis media or hearing problems. The OME group consisted of 19 children with a median age of 9 years; 15 of whom were righ...

OBJECTIVE To evaluate the effects of nimodipine on hemodynamic state, vasospasm, and short time prognosis of diffuse axonal injury (DAI) patients. METHODS In a prospective, clinical trial double blind study, 40 DAI patients with Glasgow coma scale of 5-8 were selected and randomly divided into 2 equal groups. The first group was treated with 60 mg of nimodipine every 4 hours immediately after...

The partial 16S rRNA sequence of an unknown bacterium that was originally isolated from middle ear fluids of children with persistent otitis media was determined by reverse transcription. A comparison of this sequence with sequences from other gram-positive species having low guanine-plus-cytosine contents revealed that this bacterium represents a new line of descent, for which the name Alloioc...

Mass and stiffness affect on the peculiar characteristics of transmission of the middle ear and the distinctive behavior of the cochlear mechanics. Applying the principle of the mass and stiffness, the band-pass characteristic transfer function of the middle ear has been explained. The greatest transfer function of the middle ear, approximately 24-29 dB, is observed at 1-2 kHz in both cat and h...

the Agency for Healthcare Research and Quality and the National Institute of Child Health and Human Development indicates that in most cases, inserting tubes in the eardrums—a procedure called tympanostomy— of children under age 3 who have fluid in the middle ear has no measurable effect on improving their speech, language, cognitive, or psychosocial development at age 3. Fluid in the middle ea...

CONTEXT Anatomical, physiological, and epidemiological data indicate that there may be a significant genetic component to prolonged time with and recurrent episodes of otitis media in children. OBJECTIVE To determine the genetic component of time with and episodes of middle ear effusion and acute otitis media (AOM) during the first 2 years of life. DESIGN Prospective twin and triplet cohort...

PURPOSE Although the concept of "one airway, one disease," which includes the middle ear space as part of the united airway is well recognized, the role of allergens in otitis media with effusion (OME) is not clearly understood. We aimed to investigate the effect of the interaction between Dermatophagoides farinae (Der f) and lipopolysaccharide (LPS) on the induction of epithelial inflammatory ...

We present a case of cryptococcal meningoencephalitis producing narrowing of both middle cerebral arteries on MRI/MRA, described in a 56-year-old man with a history of Wegener's granulomatosis. Diagnosis was based on the presence of cryptococcal antigen in serum and CSF. Imaging performed seven months after initial presentation demonstrated thickened enhancing leptomeninges with focal inflammat...