We propose that one can deduce very insightful information regarding the drug and fatty acid binding capacity of microemulsions through simple turbidity experiments. Pluronic F127-based oil-in-water microemulsions of various compositions were synthesized and titrated to turbidity with concentrated amitriptyline, an antidepressant drug. We observed that, above certain Pluronic F127 concentration...

Let D be a domain in the complex in-plane and let as: D —• R be a regular minimal surface. Let M(K) be the set of points tu 0. The components of M(K) are of three types: isolated points; simple analytic arcs terminating nowhere in D; analytic Jordan curves in D. Components of the third type are r...

UV irradiation induces free radical formation in the skin. UV filters and antioxidants can be used for protection. In the present work, the amphiphilic antioxidant ascorbyl palmitate has been investigated and its effectiveness against free radical formation in porcine skin determined with electron paramagnetic resonance (EPR) spectroscopy with a spin trapping technique. 5-(diethoxyphosphoryl)-5...

Small-angle neutron scattering is a powerful tool for investigating the microstructure of self-assembled systems. The domain length, d, and the correlation length, xi, are two measures of bicontinuous microemulsions that are often determined from coherent SANS spectra. Some microemulsions scatter strongly, however, so measured spectra can contain multiple coherent scattering, and neglect of tha...

A microemulsion system of docetaxel was prepared and evaluated for its solubilization capacity and oral bioavailability improvement. Based on a solubility study and pseudo ternary phase diagrams, microemulsions of about 30 nm in mean diameter were formulated with improved solubilization capacity towards the hydrophobic drug, docetaxel. The o/w microemulsion formulation (M-3) composed of Capryol...

The aim of the present study was to prepare and evaluate different formulations of Diclofenac diethylammonium in microemulsion base with a view to enhance its permeability through the skin. Various o/w and w/o microemulsions of Diclofenac diethylammonium were prepared by the spontaneous emulsification methods. Isopropyl myristate was used as oil phase, Polyoxyethylenesorbitan monooleate and Sor...

INTRODUCTION The purpose of this study was to compare the torsion and bending properties of OneShape (OS; Micro Mega, Besançon, France) and WaveOne (WO; Dentsply Maillefer, Ballaigues, Switzerland) single-file systems. METHODS The torsional strength of OS size #25, 0.06 taper and WO primary size #25, 0.08 taper was measured by using a torsiometer after fixing the apical 5 mm of the instrument...

Catalytic and spectroscopic properties of alcohol dehydrogenase from horse liver, incorporated in reversed micellar media, have been studied. Two different reversed micellar systems have been used, one containing an anionic [sodium bis(2-ethylhexyl)sulfosuccinate, AOT], the other containing a cationic (cetyltrimethylammonium bromide, CTAB) surfactant. With 1-hexanol as substrate the turnover nu...

OBJECTIVE To investigate the effect of sitting posture on lung capacity and expiratory flow (LC-EF) and lumbar lordosis. DESIGN Repeated measures on 1 group of subjects in 4 postures. SETTING Laboratory. PARTICIPANTS Seventy able-bodied volunteers. INTERVENTIONS Postures were assumed randomly: normal, with full ischial support and flat lumbar support; slumped, with the pelvis positioned...