Ongoing all-sky surveys by the eROSITA and Mikhail Pavlinsky ART-XC telescopes on-board Spectrum Roentgen Gamma (SRG) mission have already revealed over a million of X-ray sources. One them, SRGA J124404.1-632232/SRGU J124403.8-632231, was detected as new source in third (of planned eight) consecutive ART-XC. Based on properties identified optical counterpart it classified candidate binary (XRB...

Malignant gliomas have been shown to release glutamate, which kills surrounding brain cells, creating room for tumor expansion. This glutamate release occurs primarily via system xC, a Na+-independent cystine-glutamate exchanger. We show here, in addition, that the released glutamate acts as an essential autocrine/paracrine signal that promotes cell invasion. Specifically, chemotactic invasion ...

In aquatic ecosystems, the superimposition of mixing events to the light diel cycle exposes phytoplankton to changes in the velocity of light intensity increase, from diurnal variations to faster mixing-related ones. This is particularly true in coastal waters, where diatoms are dominant. This study aims to investigate if coastal diatoms differently activate the photoprotective responses, xanth...

Genetic programming starts with an initial population of computer programs composed of elementary functions and termir_als ~9, 10, 8]. Genetic operators, such as crossover and selection, are used to adapt the shape and size of the programs and evolve increasingly fit populations. This process can be viewed as a search for a highly fit computer program, Abe•t, in the whole program space A= {A1, ...

This study proposes a materials procurement contracts model to which the zero-cost collar option is applied for heading price fluctuation risks in construction.The material contract model based on the collar option that consists of the call option striking zone of the construction company(the buyer) following the materials price increase andthe put option striking zone of the material vendor(th...

BACKGROUND Juvéderm Voluma XC is a volumizing hyaluronic acid filler used for correction of age-related midface volume deficit (MVD). OBJECTIVES The effectiveness of Juvéderm Voluma XC was examined from the patient perspective. METHODS Patients with moderate to severe age-related MVD (N = 235) received Juvéderm Voluma XC. At quarterly follow-up visits for 2 years, patients rated treatment o...

The slc7a11 gene encodes xCT, an essential component of 'system xc-', a plasma membrane exchanger that imports cystine and exports glutamate. Slc7a11 is expressed primarily in the brain, but its role there is not clear. We performed behavioral tests on two different strains of homozygous slc7a11 mutant mice ('sut' and 'xCT'), as well as heteroallelic offspring of these two strains ('xCT/sut') a...