BACKGROUND Both central sensitization after peripheral tissue injury and the development of opioid tolerance involve activation of N-methyl-D-aspartate (NMDA) receptors. At subanesthetic doses the NMDA receptor antagonist xenon suppresses pain-evoked sensitization of pain-processing areas in the central nervous system. Although numerous studies describe the effect of NMDA receptor antagonists o...

A highly efficient, continuous wave 172nm Xenon excimer lamp scalable in power, size and geometry is reported. Data from a prototype device based on multiple corona discharges, operating in dense Xenon gas, confirmed the concept. Results imply that large lamps with uniform VUV-light output exceeding 100mW/cm and wall plug electrical power to VUV light conversion efficiencies approaching 50% can...

BACKGROUND Antagonists of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors have been shown not only to have neuroprotective effects but also to exhibit neurotoxic properties. In this study, we used c-Fos, a protein product of an immediate early gene, as a marker of neuronal injury to compare the neuroprotective effects of xenon and the neurotoxic properties of xenon, nitrous oxide...

We report on the first secondary and tertiary complexes of the pillar[5]arene derivative with xenon in water. We show that the chemical shift of the encapsulated xenon provides information on the type of the formed complex suggesting that has the potential to be used as a platform for NMR biosensors.

Cerebral ischemia is the leading cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Although 70% of the patients show angiographic vasospasm only 30% develop symptomatic vasospasm defined as delayed cerebral ischemia (DCI). Early detection and management of reversible ischemia is of critical importance in patients with SAH. Using a bedside Xenon enhanced comput...

BACKGROUND Nitrous oxide limits intraoperative hypothermia because the vasoconstriction threshold with nitrous oxide is higher than with equi-minimum alveolar concentrations of sevoflurane or isoflurane, presumably because of its stimulating actions on the sympathetic nervous system. Xenon, in contrast, does not cause sympathetic activation. Therefore, the authors tested the hypothesis that the...

BACKGROUND Postoperative cognitive impairment after general anaesthesia, especially in the elderly, is a well-recognized problem. Xenon, known to be an N-methyl-d-aspartate antagonist, may be advantageous. In this study, the early cognitive function in the elderly after general anaesthesia with xenon was compared with that after desflurane. METHODS After approval by the local ethical committe...

BACKGROUND Anaesthesia using xenon may be contraindicated in some situations because of its diffusion into intravascular bubbles. The expansion of air bubbles in water equilibrated with either nitrous oxide or xenon was studied. METHODS Equilibrated water was transferred to a stirred vial, closed except for a long, narrow-bore tube. Injection of an air bubble caused displacement of water alon...

Analyses of argon and xenon spectral emission data in the IR range and estimation of electron temperatures are performed on a theta pinch test article. Estimations are based on the intensity ratio technique using collisional-radiative models. Tests performed on a pulsed xenon plasma at an energy of 80 joules, neutral back-fill pressures of 10−2 to 10−1 Torr, and vacuum discharge frequency of 46...

The expected emission spectra of xenon plasma have been studied for different conditions using FLYCHK code. Expected xenon plasma spectra at certain electron temperature range have been plotted. The suitable electron temperature ranges for xenon plasma soft X-ray emission and extreme ultraviolet emission have been investigated. The X-ray ratio curves for various electron temperatures with proba...