Suggested scheme for the treatment of onychomycosis A stepped therapeutic approach to the treatment of onychomycosis is suggested. The risks of failure of treatment include the fungal involvement of the lunula portion, the lateral edge of the nail and the subungual area. Infection of the subungual area may lead to extensive onycholysis or dermatophytoma presenting as a hard subungual mass or as...

Patients with nail-patella syndrome often suffer from a nephropathy, which ultimately results in chronic renal failure. The finding that this disease is caused by mutations in the transcription factor LMX1B, which in the kidney is expressed exclusively in podocytes, offers the opportunity for a better understanding of the renal pathogenesis. In our analysis of the nephropathy in nail-patella sy...

BACKGROUND Cutaneous T-cell lymphoma (CTCL) encompasses a broad range of lymphoproliferative diseases affecting the skin and can be clinically misleading due to its variable presentation. Nail alterations commonly appear in advanced-stage mycosis fungoides and true Sézary syndrome; however, they may be present in any stage of the disease. Although proper recognition of nail involvement in CTCL ...

Nail-patella syndrome is a rare disorder, which is inherited as an autosomal dominant trait. This condition is also known as hereditary osteo-onychodysplasia or Fong's syndrome. Posterior iliac horns are commonly found in this syndrome and are considered pathognomonic. In this report, we describe the appearance, location, and structure of iliac horns with respect to radiography and magnetic res...

Background: Tooth and Nail Syndrome (TNS) is a rare genetic disorder and one of the common types of Ectodermal Dysplasias (ED). Fried and Witkop Syndromes are two subtypes with similar clinical and radiological features with a difference in the inheritance pattern. ?just state the genetic difference. The condition is particularly of interest to dentists because of the challenges in prosthetic r...

Introduction A 43 year-old woman su ered a chronic renal failure secondary to chronic primary glomerulopathy that manifested 16 years ago. After 2 years of regular Nail–patella syndrome or hereditary osteoonychodysplasia, is an autosomal dominant syndrome programme of dialysis, she received a cadaveric renal allograft. The donor was a 18-year-old man who died with variable expression and penetr...