BACKGROUND Kearns-Sayre syndrome (KSS) is a rare mitochondrial cytopathy, first described at Mayo Clinic in 1958. AIMS We aimed to define patient and disease characteristics in a large group of adult and pediatric patients with KSS. METHODS We retrospectively searched the Mayo Clinic medical index patient database for the records of patients with KSS between 1976 and 2009. The 35 patients i...

BACKGROUND To report the clinical, electrophysiological and the anatomical findings in a patient with Kearns-Sayre syndrome (KSS). CASE PRESENTATION We present the case of a 55-year-old female with KSS, who developed systemic features and ocular manifestations as ophthalmoplegia and retinal dysfunction, that were corroborated by electrophysiological test and High Definition Spectral Domain Op...

We read the article by Leal et al. with interest about a 17-year-old male with Kearns–Sayre syndrome (KSS), diagnosed upon the clinical presentation, instrumental findings and the muscle biopsy findings [1]. Despite some peculiarities of the phenotype, the presentation at onset was mild and the further course uneventful. We have the following comments and concerns. The main disadvantage of this...

OBJECTIVE To assess the effect of a 12-hour shift on mood states and sleepiness at the beginning and end of the shift. METHOD Quantitative, cross-sectional and descriptive study.It was conducted with 70 neonatal intensive care unit nurses. The Brunel Mood Scale (BRUMS), Karolinska Sleepiness Scale (KSS), and a socio-demographic profile questionnaire were administered. RESULTS When the KSS a...

Zusammenfassung Kühlschmierstoff (KSS)-strömungen werden in Schleifprozessen eingesetzt, um Schleifbrand am Werkstück zu verhindern. Bislang wurde die KSS-Zufuhr heuristisch optimiert. Um eine zielgerichtete KSS-Strömungsoptimierung ermöglichen, wird erstmals optische schleifscheibennahe Messung von KSS-Strömungsfeldern mittels Particle Image Velocimetry (PIV) und durch Nachverfolgung Mustern S...

Following the emergence of Kim and Barbulescu’s new number field sieve (exTNFS) algorithm at CRYPTO’16 [21] for solving discrete logarithm problem (DLP) over the finite field; pairing-based cryptography researchers are intrigued to find new parameters that confirm standard security levels against exTNFS. Recently, Barbulescu and Duquesne have suggested new parameters [3] for well-studied pairin...

The present study of sleepiness and accident risk in a HI-FI car simulator aimed to provide subject-level relative risks (RR) with 95% confidence intervals (CI) for different levels of subjective sleepiness measured with the Karolinska Sleepiness Scale (KSS), 1 = very alert, 9 = very sleepy, fighting sleep, an effort to staying awake. Five male and five female shift workers, mean age 37 years, ...

about the clinical presentation and central nervous system (CNS) imaging in 19 patients with Kearns-Sayre syndrome (KSS), of whom 12 were genetically confirmed. We have the following comments and concerns. The main disadvantage of the study was that the diagnosis was not genetically confirmed in all patients and mitochondrial DNA (mtDNA) deletion was detected in only 63% patients. What was the ...

Abstract. This paper presents a modification of Krylov subspace spectral (KSS) methods, which build on the work of Golub, Meurant and others, pertaining to moments and Gaussian quadrature to produce high-order accurate approximate solutions to variable-coefficient time-dependent PDEs. Whereas KSS methods currently use Lanczos iteration to compute the needed quadrature rules, our modification us...

Microfracture (MFX) is a common operation for articular cartilage lesions. Data for patients who underwent total knee arthroplasty (TKA) after previous MFX are limited. The purpose of this study was to determine the outcomes, complications, and factors that influence outcomes in patients with previous MFX compared with those without previous MFX. Between 2005 and 2014, twenty-one TKAs were perf...