Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of a cystine knot protein family that includes Cerberus and Gremlin. First isolated in a screen to identify genes down-regulated in transformed rat fibroblasts, DAN has subsequently been cloned in Xenopus, mouse, and human. Overexpression of DAN suppresses the transformed phenotype and retards the cell's entry in...

The Dan family of transforming growth factor beta antagonists is a large, evolutionarily conserved family of proteins. Little is known about either the specificity of these antagonists or the biological roles of these proteins. We have characterized Dan, the founding member of this family, with regard to both its biochemical specificity and its biological roles. Although DAN is not an efficient...

To assess the occurrence and nature of sleep-disordered breathing (SDB) in 26 adult, nonobese diabetics (18 with autonomic neuropathy (DAN+) (age 45 (41-50) yrs; body mass index (BMI) 24.1 (22-26) kg x m(-2)) and eight without autonomic neuropathy (DAN-) (age 45 (35-55) yrs; BMI 24.8 (23-26) kg x m(-2))) overnight full sleep studies and measurements of central and peripheral carbon dioxide (CO2...

Seiring kemajuan dalam teknologi ponsel, Smartphone memiliki kemampuan untuk mengakses layanan web dalam aplikasi pengguna berinteraksi untuk mengambil dan mengirim informasi dari dan ke layanan web. Karenanya, Smartphone semakin meningkat popularitasnya. Pemanfaatan layanan web baru dan layanan web yang telah ada juga akan tumbuh pesat. Makalah ini memberikan perbandingan dari dua jenis utama ...

Abstrak Shape Memory Alloy (SMA) adalah salah satu jenis aktuator yang sedang banyak dipelajari pada aplikasi skala mikro dan nano. Namun di sisi lain, pengembangan pengendalian dalam skala ini masih perlu pengembangan dan penelitian lebih lanjut. Artikel ini mempresentasikan hasil evaluasi tanggapan pergerakan kendali kalang tertutup dari TiNi SMA dalam bentuk spring yang dikendalikan kompensa...

We have used diabetic autonomic neuropathy as a model of chronic pulmonary denervation to study the ventilatory response to incremental exercise in 20 diabetic subjects, 10 with (Dan+) and 10 without (Dan-) autonomic dysfunction, and in 10 normal control subjects. Although both Dan+ and Dan- subjects achieved lower O2 consumption and CO2 production (VCO2) than control subjects at peak of exerci...

To present the application of the XOR Theorem to learning theory we rst give the following two de nitions. Let F be a class of boolean functions and let > 0. A strong learning algorithm for F over the uniform distribution queries the function f : f0; 1gn ! f0; 1g and outputs, with probability at least 1 , a circuit C such that Pr[f(x) 6= C(x)] < 1 nO(1) where Pr is the uniform distribution. The...

Anticorrelation between the default network (DN) and dorsal attention network (DAN) is thought to be an intrinsic aspect of functional brain organization reflecting competing functions. However, the effect size of functional connectivity (FC) between the DN and DAN has yet to be established. Furthermore, the stability of anticorrelations across distinct DN subsystems, different contexts, and ti...

Serangga jika mengigit atau menyengat, memasukkan secret air liur atau racun sengat yang dapat menimbulkan reaksi alergis. Jenis reaksi yang ditimbulkan akibat gigitan atau sangatan serangga bagi penderita tertentu sangat bergantung kepada spesies serangga dan macam alergan. Tanda-tanda dan gejala klinis reaksi alergis akibat gigitan atau sengatan serangan dapat berupa gatal-gatal, pembengkakan...

Seorang pasien laki-laki 27 tahun dengan leukemia mielositik kronik dengan pengobatan hidroksi urea yang tidak teratur, datang dengan keluhan benjolan di pangkal paha kiri disertai rasa nyeri tumpul. Pemeriksaan darah menunjukkan lekosit 125.000/mm3 dengan 13% metamielosit, 8% mielosit, 1% promielosit dan 3% sel batang. Biopsi aspirasi jarum halus menunjukkan sebagian besar sel mieloblas dan se...