An alternative interface for flow injection-capillary electrophoresis based on electrokinetic injection is described. The interface basically consists of tubular platinum and a commercially available standard tee connector. The tubular platinum works as not only an electrode, but also a waste outlet of a split sample solution. The availability of the proposed interface is evaluated by the separ...

We recently reported acupuncture sample injection that leads to reproducible injection of nL-scale sample segments into a polydimethylsiloxane (PDMS) microchannel for microchip capillary electrophoresis. The advantages of the acupuncture injection in microchip capillary electrophoresis include capability of minimizing sample loss and voltage control hardware and capability of introducing sample...

Sweeping is an effective and convenient way for online sample preconcentration in micellar electrokinetic chromatography. The usual procedure includes a hydrodynamic injection step carried out by applying pressure to the sample vial followed by the subsequent sweeping and separation processes. The injected sample volume is limited by the dimensions of the capillary because a part of the capilla...

A mathematical model and computer code for simulat ing electrokinetic fluid and sample manipulations in microfabricated fluidic devices (microchips) are described. The model accounts for mass transport mechanisms such as electrophoretic migration, bulk fluid motion due to electroosmosis, and diffusion. The interactive computer program implementing the model is capable of handling different chan...

A novel pressure-driven sample injection method was developed as an alternative to electrokinetic injection, and electrophoretic separation was carried out on a microfabricated device employing this method. This method enables a defined volume of liquid dispensing, followed by instantaneous injection driven by pneumatic pressure, greatly simplifying the injection procedure. A particular microst...