Acetaminophen (APAP) hepatotoxicity is the most common cause of drug-induced liver injury and N-acetylcysteine (NAC) is the primary antidote of APAP poisoning. Wuzhi tablet (WZ), the active constituents well identified and quantified, is a preparation of an ethanol extract of Schisandra sphenanthera and exerts a protective effect toward APAP-induced hepatotoxicity in mice. However, the clinical...

Schisandra sphenanthera is widely used as a tonic and restorative in many countries to enhance the function of liver and other organs. Wuzhi tablet (WZ) is a preparation of an ethanol extract of Schisandra sphenanthera. Our previous study demonstrated that WZ exerted a protective effect toward acetaminophen (APAP)-induced hepatotoxicity. However, the molecular mechanisms of this protection rema...

Schisandra sphenanthera is widely used as a tonic and restorative in many countries to enhance the function of liver and other organs. Wuzhi tablet (WZ) is a preparation of an ethanol extract of Schisandra sphenanthera. Our previous study demonstrated that WZ exerted a protective effect toward acetaminophen (APAP)-induced hepatotoxicity. However, the molecular mechanisms of this protection rema...

Let F : (R,0)→(R,0) and g : (R,0)→R be analytic germs, let Br ⊂ R be a closed ball of small radius centred at the origin, and let Wz = F −1(z) ∩ Br. Let λ(g;Wz) = ∑ p(−1), where λ(p) is the Morse index at a critical point p of a Morse function which approximates g|Wz. For F and g satisfying some natural assumptions, we shall show that there is a finite family of analytic germs θi(z) such that λ...

Possible prevention and therapeutic intervention strategies to counteract acetaminophen (APAP) hepatotoxicity would be of great value. Wuzhi tablet (WZ, extract of Schisandrae sphenanthera) possesses hepatoprotective effects against hepatitis and the hepatic dysfunction induced by various chemical hepatotoxins. In this study, the protective effect of WZ on APAP-induced hepatic injury was evalua...

We previously reported that the ethanol extract of Schisandra sphenanthera [Wuzhi (WZ) tablet] significantly protects against acetaminophen-induced hepatoxicity. However, whether WZ exerts a protective effect against cholestasis remains unclear. In this study, the protective effect of WZ on lithocholic acid (LCA)-induced intrahepatic cholestasis in mice was characterized and the involved mechan...

III-V Nanowires (NWs) grown with metal-organic chemical vapor deposition commonly show a polytypic crystal structure, allowing growth of structures not found in the bulk counterpart. In this paper we studied the radial overgrowth of pure wurtzite (WZ) GaAs nanowires and characterized the samples with high resolution X-ray diffraction (XRD) to reveal the crystal structure of the grown material. ...

WZ Sge-type dwarf novae are characterized by long recurrence times of outbursts ( 10 yr) and short orbital periods (. 85 min). A significant part of WZ Sge stars may remain undiscovered because of low outburst activity. Recently, the observed orbital period distribution of cataclysmic variables (CVs) has changed partly because outbursts of new WZ Sge stars have been discovered routinely. Hence,...

Wyner–Ziv (WZ) coding of video utilizes simple encoders and highly complex decoders. A transcoder from a WZ codec to a traditional codec can potentially increase the range of applications for WZ codecs. We present a transcoder scheme from the most popular WZ codec architecture to a differential pulse code modulation/discrete cosine transform codec. As a proof of concept, we implemented this tra...

Liver regeneration after surgical liver resection is crucial for the restoration of liver mass and the recovery of liver function.Schisandra sphenanthera extract (Wuzhi tablet, WZ) is a preparation of an extract from the dried ripe fruit of Schisandra sphenanthera Rehd. et Wils, a traditional hepatoprotective herb. Previously, we found that WZ could induce liver regeneration-related genes again...