Peter L. Tyack, Andreas Fahlman, Michael Moore, and Darlene Ketten Woods Hole Oceanographic Institution 266 Woods Hole Road, MS #50 Woods Hole MA 02543 phone: (508) 289-2818 fax: (508) 457-2041 email: [email protected] phone: (508) 289-3463 fax: (508) 457-2041 email: [email protected] phone: (508) 289-3228 fax: (508) 457-2041 email: [email protected] phone: (508) 289-2731 fax: (508) 457-2041 email:...

فارابی و ابن‌سینا در شمار برجسته‌ترین نام‌ آشناترین فیلسوفان مشایی عرصة مباحث فلسفی عقلی‌اند، بنیان‌های فکری نظام مشائی جهان اسلام براساس مبانی عقلی اندیشه‌های این دو فیلسوف بزرگ بنا نهاده شده است، نوع نگرش به حکمت عملی زمینه‌ساز پرسش‌ها تردیدهایی این‌باره تا آنجا که برخی چنین پنداشته‌اند پی‌جویی از مسائل دغدغة نبوده مقالة حاضر کوشیده است با ارائه ارزیابی دیدگاه دربارة تبیین نماید افزون بر مباد...

The cytotoxic effect of tamoxifen (TAM) was investigated in the T-289 melanoma cell line, as well as the 289 DDP3 cisplatin (DDP)-resistant and the 289 TAM6 TAM-resistant variant melanoma cell lines to determine the effect of drug resistance on synergy. T-289 melanoma cells were made DDP or TAM resistant through chronic exposure to increasing concentrations of the respective drugs. Whereas DDP ...

PAULO MONTEIRO J. , COSTA MANUEL S. 2 Ph.D. in Hydrogeology, Auxiliary Professor Universidade do Algarve, FCMA, GeoSystems Centre CVRM (IST) Campus de Gambelas, 8005-139 Faro, Phone: 351 289 800900; Fax: 351 289 818353 [email protected] Senior Agronomic Engineer, Private Consultant and Ph.D. Student Algarve University, FERN Faculty of Engineering of Natural Resources Campus de Gambelas, 8005-139...

We used the secreted TSH receptor (TSHR) ectodomain variant TSHR-289 (truncated at amino acid residue 289 with a 6-histidine tail) to investigate properties of TSHR autoantibodies in Graves' disease. Sequential concanavalin A and Ni-chelate chromatography extracted milligram quantities of TSHR-289 (approximately 20-40% purity) from the culture medium. Nanogram quantities of this material neutra...

The [Het-s] prion of the fungus Podospora anserina propagates as a self-perpetuating amyloid form of the HET-s protein. This protein triggers a cell death reaction termed heterokaryon incompatibility when interacting with the HET-S protein, an allelic variant of HET-s. HET-s displays two distinct domains, a N-terminal globular domain and a C-terminal unstructured prion-forming domain (residues ...

INTRODUCTION To assess the reliability of short versions of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI). METHODS A short form of the ANU-ADRI (ANU-ADRI-SF) was developed by assessing risk and protective factors with single questions where possible and with short forms of sub-questionnaires where available. The tick box form of the ANU-ADRI (ANU-ADRI-TB) was de...

Anu Suomalainen (Wartiovaara) completed her MD degree in 1991, and in 1993 defended her PhD thesis on mitochondrial DNA mutations in diseases, at the University of Helsinki, Finland. She relocated to McGill University in 1998, and returned to Finland in 2001. Her research group has been established in BiomedicumHelsinki since 2001, and belongs to the FinMIT Centre of Excellence of the Academy o...

neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and some ischemia-induced dementia. Ideal treatment and prevention for these diseases would interrupt the degenerative procedure specific to each disease, such as the trial of a b-secretase inhibitor to reduce the production of toxic amyloid b peptides that play key roles in Alzheimer’s disease. However, there is stil...