Background and Aims: Previous investigations have revealed that microRNAs (miRNAs) can function as oncogenes or tumor suppressors in chronic lymphocytic leukemia (CLL) and that the expression of miRNAs, such as miR-485-3p changes in several illnesses. This study was designed to determine the expression level of miR-485-3p and its target FOXD3 in CLL patients and controls to identify if this miR...

Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs that are usually 18-24 nucleotides long, which may have a pivotal role in the expansion of many complex diseases. The objective of this study was to evaluate the transcript levels of miR-193b-3p and miR-376a-3p in relapsing-remitting multiple sclerosis (RRMS) ...

abstract effect of selection index in four iranian commercial lines (107, 110, 153 and 154) on performance of their hybrids including 107 ×110, 110×107, 153×154 and 154×153 was investigated. selection index program was performed on all 3p commercial lines during 9 generations. next generation parents of 3p lines were selected in each generation, by construction of selection matrix based on heri...

Background Studies have shown that the microRNA miR-302 can affect the proliferation, migration and cell cycle progression of endometrial carcinoma (EC). miR-302 clusters have been shown to play an important role in the proliferation and differentiation of cancer cells and in their tumorigenicity. Subjects and methods In this study, we detected the expression of genes through quantitative rev...

Two-body open charm strong decays of the $2P$ and $3P$ charmonium states are studied by Bethe-Salpeter(BS) method combined with $^3P_0$ model. The wave functions mass spectra obtained solving BS equation relativistic correction. decay widths relative ratios calculated. Comparing our results experimental data, we obtain some interesting results. Considering $X^*(3860)$ as $\chi_{c0}(2P)$, total ...

MicroRNAs have emerged as important regulators of the metastatic process. In addition, circulating miRNAs appear to be surprisingly stable in peripheral blood making them ideal noninvasive biomarkers for disease diagnosis. Here, we performed a proof-of-principle study investigate expression profile and their association with lymph node status early breast cancer patients. Sentinel was detected ...