نتایج جستجو برای: روش ubc
تعداد نتایج: 370759 فیلتر نتایج به سال:
Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.
Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded common variants at 12 loci that associate with risk of the disease. We report here the results of a GWAS of UBC including 1670 UBC cases and 90 180 controls, followed by replication analysis in additional 5266 UBC cases and 10 456 controls. We tested a dataset containing 34.2 million variants, generated by imput...
Ubiquitous Business Communities (UBC) are information processing systems that offer people the possibility to connect to networks, any time independently from location and computing platforms, which are sensitive to the users ́ contexts. UBC allow participants to exchange information and enhance business transactions. These systems may act as market organizers and may affect millions of producer...
اهداف اصلی این پایان نامه بررسی فلسفه ضوابط جدید در آیین نامه ubc 97 و تاثیر آنها بر روی نیروهای ناشی از زلزله و مقایسه مقدار نیروی ناشی از زلزله در آیین نامه های 2800 ایران (ویرایش دوم) و ubc 97 می باشند. برای نیل به اهداف فوق این پایان نامه در چهار قسمت ((بررسی ضوابط و معیارهای آیین نامه های 2800 ایران) (ویرایش دوم) و ubc 94 و مقایسه آنها با یکدیگر))، ((بررسی ضوابط آیین نامه ubc 97 و تشری...
In uremia, muscle wasting involves increased glucocorticoid production and activation of the ubiquitin-proteasome proteolytic pathway, including increased expression of ubiquitin. Previously, we reported that glucocorticoids stimulate ubiquitin transcription by a mechanism involving Sp1 in L6 muscle cells (Marinovic AC, Zheng B, Mitch WE, Price SR. J Biol Chem 277: 16673-16681, 2002). This find...
BACKGROUND Hotspot mutations in the promoter of the gene coding for telomerase reverse transcriptase (TERT) have been described and proposed to activate gene expression. OBJECTIVES To investigate TERT mutation frequency, spectrum, association with expression and clinical outcome, and potential for detection of recurrences in urine in patients with urothelial bladder cancer (UBC). DESIGN, SE...
Department of Neurology, University of British Columbia (UBC), Vancouver, British Columbia, Canada Department of Medicine, UBC, Vancouver, British Columbia, Canada Division of Infectious Disease Department of Medicine, UBC, Vancouver, British Columbia, Canada Women’s Health Research Institute, BC Women’s Hospital, Vancouver, British Columbia, Canada Oak Tree Clinic, BC Women’s Hospital, Vancouv...
M. Krausz1,2,4; M. Vogel3; M. Nikoo1 1Institute of Mental Health, Department of Psychiatry, University of British Columbia (UBC), Vancouver, BC, Canada; 2School of Public and Population Health, University of British Columbia (UBC), Vancouver, BC, Canada; 3Division of Substance Use Disorders, Psychiatric Hospital of the University of Basel; 4Centre for Health Evaluation and Outcome Sciences, Uni...
OBJECTIVE Several commercial point-of-care (POC) tests are available for urine-based detection of bladder cancer (BC). However, these tests are restricted to dichotomized results (positive or negative), which limits their diagnostic value. Quantitative protein-based tests offer improved risk stratification but require complex methods restricted to specialized centers. Recently, the first quanti...
OBJECTIVE The objective of this study was to examine the association between diabetes, and both urinary bladder cancer (UBC) risk and mortality. METHODS We conducted a retrospective cohort study using data from the UK Clinical Practice Research Datalink (CPRD) linked to the Office of National Statistics (ONS). Patients diagnosed with diabetes mellitus type 1 or 2, or using antidiabetic drugs ...
Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first exon, first intron and a small part of the second exon of UBC. Because splicing can occur after transcription of the vector genome during vect...
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