Nitrate reductase (nar) A, B and E mutants of Escherichia coli with plasmids carrying Klebsiella pneumoniae nitrogen fixation (nif) genes reduced acetylene independently of added molybdate, but nar D mutants showed pleiotropic dependence on the concentration of added molybdate for expression of both nar and nif. No complementation of nar mutations by nif occurred; nitrite but not nitrate repres...

Addition of ethylene to Mo(NAr)(CHCMe2Ph)(OHIPT)(Pyr) (NAr = N-2,6-i-Pr2C6H3, OHIPT = O-2,6-(2,4,6-i-Pr3C6H2)2C6H3, Pyr = NC4H4) led to the trigonal bipyramidal metallacyclobutane complex, Mo(NAr)(C3H6)(OHIPT)(Pyr), in which the imido and aryloxide ligands occupy axial positions. Mo(NAr)(C3H6)(OHIPT)(Pyr) loses ethylene to give isolable Mo(NAr)(CH2)(OHIPT)(Pyr). W(NAr)(CH2)(OTPP)(Me2Pyr) (OTPP ...

Estrogen receptor (ER) antagonists such as tamoxifen (Tam) have been used successfully to treat ER+ breast cancers for more than 30 years. Unfortunately, long term use of Tam can result in resistance. Tam resistance is associated with the activation of growth factor signaling pathways that promote cell proliferation and survival. The mitogen-activated protein kinase (MAPK), is up-regulated in T...

Plant population density (PPD) and nitrogen (N) application rate (NAR) are two controllable factors in cotton production. We conducted field experiments to investigate the effects of PPD, NAR and their interaction (PPD × NAR) on yield, N uptake and N use efficiency (NUE) of cotton using a split-plot design in the North China Plain during 2013 and 2014. The main plots were PPDs (plants m-2) of 3...

We compared the rise in nasal airway resistance (NAR) provoked by topical application of substance P (SP) and of methacholine (MCH) in seventeen patients suffering from rhinitis and fourteen control subjects. Challenges with SP or MCH were separated by a week or more. NAR was measured by posterior rhinomanometry before and 10 min after intranasal administration of SP (10-40 nmol) or MCH (3-12 m...

Introduction In contrast to the significant number of studies indicating the impairment of QoL in AR, the degree of impairment in Quality of Life (QoL) in NAR remains underexposed. Again in contrast to AR, almost no evidence-based therapies for NAR patients exist. We assessed QoL in NAR compared to healthy controls and AR patients as positive controls and investigated whether the use of treatme...

The resurgent Na(+) current (I(NaR)) is a component of neuronal voltage-dependent Na(+) currents that is activated by repolarization and is believed to result from an atypical path of Na(+)-channel recovery from inactivation. So far, I(NaR) has only been identified in a small number of central neuronal populations in the cerebellum, diencephalon, and brainstem. The possible presence and roles o...

Addition of an equal molar quantity of R- (R = Me, SiMe3) to complex (Nacnac)Ti=NAr(OTf) (Nacnac- =[ArNC(tBu)]2CH, Ar = 2,6-iPr2C6H3) forms the imido alkyl (Nacnac)Ti=NAr(R), which can be readily protonated to afford [(Nacnac)Ti=NAr(L)]+ (L = THF, Et2O, eta1-C6H5NMe2), or treated with B(C6F5)3 to afford the zwitterion (Nacnac)Ti=NAr(micro-CH3)B(C6F5)3.

Fusarium oxysporum JCM11502 expresses a denitrifying (nitrate (NO(3)(-))-respiring) mechanism and can thrive under oxygen (O(2)) limitation. The fungus reduces NO(3)(-) to nitrite at the initial step of denitrification. In this study, we cloned the gene coding NADH-NO(3)(-) reductase (NADH-Nar) (niaD) from F. oxysporum JCM11502. The niaD gene complemented the defective NO(3)(-) assimilation by ...

AIM To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl4)-induced liver fibrosis. METHODS Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a control group (n = 8) that received 0.7% carboxy methyl-cellulose (NAR vehicle) 1 mL/daily p.o.; (2) a CCl4 group (n = 8) that received 400 mg of C...