cept can serve as a basis for identifying subgroups that are in need of programmatic action. Unmet need rises as more women would like to control their fertility but for various reasons are unable to do so, and it falls as more start practicing contraception. However, high levels of unmet need in a country do not necessarily reflect program failure, nor do low levels always indicate program suc...

This chapter surveys the main approaches developed to date to endow robots with the ability to learn from human guidance. The field is best known as robot programming by demonstration, robot learning from/by demonstration, apprenticeship learning and imitation learning. We start with a brief historical overview of the field. We then summarize the various approaches taken to solve four main ques...

The adsorption behavior of ions at liquid–vapor interfaces exhibits several unexpected yet generic features. In particular, energy and entropy are both minimum when the solute resides near the surface, for a variety of ions in a range of polar solvents, contrary to predictions of classical theories. Motivated by this generality, and by the simple physical ingredients implicated by computational...

Targeted glycoproteomics is an effective way to discover disease-associated glycoproteins in proteomics and serial affinity chromatography (SAC) using lectin and glycan-targeting antibodies shows glycan diversity on the captured glycoproteins. This study suggests a way to determine glycan heterogeneity and structural analysis on the post-translationally modified proteins through serial affinity...

Clinical reports indicate that cardiotoxicity due to donepezil can occur after coadministration with cilostazol. We speculated that the concentration of donepezil in heart tissuemight be increased as a result of interactionwith cilostazol at efflux transporters suchasP-glycoprotein (P-gp, ABCB1) and breast cancer resistance protein (BCRP, ABCG2), which are expressed inmany tissues including the...