Methods In a consecutive cohort of 58 patients referred for clinical enhanced cardiac MR, bh-LGE and moco-LGE were collected contemporarily with identical image parameters using a 3.0T scanner. The moco-LGE was acquired just after the bh-LGE while the patients were asked to breathe freely. Images were randomized and scored for image quality (1very poor and not analyzable, 2-poor, 3-acceptable, ...

Background Late gadolinium enhancement (LGE) cardiac MRI is the clinical gold standard for non-invasive assessment of myocardial viability and plays an important role in guiding catheter ablation of ventricular tachycardia (VT). The majority of VT patients have implanted cardiac devices such as implantable cardioverter defibrillators (ICDs). The presence of ICDs gives rise to strong off-resonan...

BACKGROUND Reproducibility data of the extent and patterns of late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) is limited. OBJECTIVE To explore the reproducibility of regional wall thickness (WT), LGE extent, and LGE patterns in patients with HCM assessed with cardiac magnetic resonance (CMR). METHODS The extent of LGE was assessed by the number of segments with LGE, a...

BACKGROUND Our study aimed to investigate both the clinical implications of late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) and the relation of LGE to clinical findings in patients with Takotsubo cardiomyopathy (TTC). METHODS We evaluated 20 consecutive patients (2 men, 18 women; median age, 77 years; interquartile range [IQR] 67-82 years) who were admitted to our...

BACKGROUND Although cardiovascular magnetic resonance (CMR) is showing increasingly diagnostic potential in left ventricular non-compaction (LVNC), relatively little research relevant to CMR is conducted in children with LVNC. This study was performed to characterize and compare CMR features and clinical outcomes in children with LVNC with and without late gadolinium enhancement (LGE). METHOD...

BACKGROUND In hypertrophic cardiomyopathy (HCM), heterogeneous myocardial hypertrophy and fibrosis are responsible for abnormalities of left ventricular (LV) function. We aimed to characterize LV global and regional myocardial mechanics in HCM, according to segmental hypertrophy and fibrosis. METHODS AND RESULTS Fifty-nine patients with HCM underwent standard echocardiography, 3-dimensional s...

Background Fibrosis after myocardial damage can be determined by cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE). We studied whether ventricular LGE is visible in the ventricles of pediatric and adolescent TOF (tetralogy of Fallot) patients by measuring LGE and investigating whether fibrosis correlated with right ventricular volume, pulmonary regurgitation, N-terminal pr...

Background Catheter-based atrial fibrillation (AF) therapy often uses cryo-balloon ablation of pulmonary vein (PV) ostia to achieve rhythm control. Prior studies suggest the ability of late gadolinium enhancement cardiac MRI (LGE-MRI) to visualize radiofrequency-induced scar. The optimal time after therapy to visualize cryo-ablation lesions is unknown. This study evaluates the relationship betw...

BACKGROUND Duchenne muscular dystrophy (DMD), an X-linked disorder affects approximately 1 in 5000 males, is universally associated with heart disease. We previously identified myocardial disease by late gadolinium enhancement (LGE) in DMD subjects at various stages of disease, but the true prevalence is unclear. Cardiovascular magnetic resonance (CMR) is well established for both assessment of...