Foot-and-mouth disease (FMD) is a contagious viral disease of livestock with significant economic effect. It is prevalent in various regions of Asia, Africa, and South America. The causative agent of this disease is called foot-and-mouth disease virus (FMDV), which is a member of Aphthovirus genus. Vaccination is an effective technique to prevent the complications of FMD and to eradicate the di...

OBJECTIVES Our aim was to analyze flow-mediated dilation (FMD) time-course in response to forearm occlusion in the clinical setting. METHODS AND RESULTS In 50 asymptomatic subjects, monitoring software measuring continuous beat-to-beat change in brachial artery diameter was used to determine FMD magnitude in percentage change in peak diameter from baseline (FMD-DeltaD), time to peak diameter ...

BACKGROUND Flow-mediated vasodilation (FMD) of the brachial artery has been used for the assessment of endothelial function. Considering the mechanism underlying the vasodilatory response of the brachial artery to reactive hyperemia, hyperemic shear stress (HSS), a stimulus for FMD; nitroglycerine-induced vasodilation (NID), an index of endothelium-independent vasodilation; and baseline brachia...

in the present study the effect of the locally produced genetic adjuvant of ginea pig specific cpg-motif-containing oligodeoxynucleotide (cpg-odn) in an inactivated fmd virus vaccine was evaluated. boosting the ginea pigs with fmd vaccine along with cpg-odn adjuvant produced relatively higher ratio (5-fold) of fmdv-specific igg2a / igg1 than those vaccinated in the absence of cpg-odn. the neutr...

The paper presents a description of the FMD BioPortal biosurveillance system (http://fmd.ucdavis.edu/bioportal/) that is currently operating to capture, analyze, and disseminate global data on foot-and-mouth (FMD) disease. The FMD BioPortal makes available to users world-wide FMD-related data from the Institute for Animal Health at Pirbright, England. The system’s tools include those for tabula...

BACKGROUND The SCORE system is a simple, currently recommended method of cardiovascular risk assessment. The aim of this study is to determine the relationship between SCORE risk and intima media thickness (IMT) and flow mediated dilatation (FMD) in a low risk population. METHODS 119 people (59 men) without known cardiovascular disease and estimated by means of SCORE system risk < 5%, were in...