نتایج جستجو برای: قواعد 458
تعداد نتایج: 10906 فیلتر نتایج به سال:
Tacrolimus requires close therapeutic drug monitoring because of its narrow therapeutic index and marked interindividual pharmacokinetic variation. In this study, we investigated the associations of polymorphisms in the gene encoding 11b-hydroxysteroid dehydrogenase type 1 (HSD11B1) with tacrolimus concentrations in Chinese renal transplant recipients during the early posttransplantation stage....
In "Mathematical Games" in the December 1966 issue of Scientific American, Martin Gardner made the following statement regarding Pascals triangle: "Almost anyone can study the triangle and discover more properties, but it is unlikely that they will be new, for what is said here only scratches the surface of a vast literature." But, of course, many new results have been discovered since 1966 and...
Deregulated phosphatidylinositol 3-kinase (PI3K) signaling pathway is widely implicated in tumor growth and resistance to chemotherapy. While a strong rationale exists for pharmacological targeting of PI3K, only a few proof-of-principle in vivo efficacy studies are currently available. PWT-458, pegylated-17-hydroxywortmannin, is a novel and highly potent inhibitor of PI3K in animal models. Upon...
INTRODUCTION.................................................................. 442 FINE STRUCTURE OF FLAGELLA.................................................. 443 Comparative Anatomy of the Flagella of Bacteria and Other Organisms ......... 443 Chemical and Physical Properties of Bacterial Flagella........................ 444 Electron Microscope and X-Ray Diffraction Studies of Bacterial Flage...
Disorders, Agents, or Events Associated with Decreased Transport of Taste Stimuli to the Taste Buds, 458 Disorders, Agents, or Events Associated with Damage to Taste Sensorineural Structures, 458 Conclusions, 460 References, 460 Olfactory Dysfunction and Its Causes, 450 Disorders Associated with Decreased Transport of Odorant Molecules to the Olfactory Neuroepithelium,453 Disorders, Agents, or ...
The phantom midge, Chaoborus, is a dipteran, the larvae of which occur in many freshwater habitats and are known to be vulnerable to predation by fish. The hypothesis was tested that ovipositing imagines of Chaoborus use chemical cues to detect predatory fish and avoid depositing eggs into waterbodies containing fish kairomones. The experimental setup consisted of cages with two small water-fil...
The purpose of this study was to investigate the capability Streptococcus thermophilus TISTR 458 on hyaluronic acid (HA) production by using various carbon sources including glucose, sucrose and sugarcane molasses. HA determined a turbidity assay precipitation with cetyltrimethylammonium bromide (CTAB) sugar content analysed sulphuric acid-UV spectrophotometry method. results showed that S. pro...
The importance of membrane-bound PGE synthase 1 (mPGES1) in the regulation of renal function has been examined in mPGES1-deficient mice or by evaluating changes in its expression. However, it is unknown whether prolonged mPGES1 inhibition induces significant changes of renal function when Na(+) intake is normal or low. This study examined the renal effects elicited by a selective mPGES1 inhibit...
CPT-11 [7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin or Irinotecan] is a carbamate prodrug that is activated in vivo by carboxylesterase (CES)-2 to SN-38 (7-ethyl-10-hydroxycamptothecin), a potent topoisomerase I inhibitor. There is high interindividual variation when CPT-11 is used in the treatment of colorectal cancer. Several splice variants of CES2 are reported in the ...
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