The goal of this brief review is to address the role of the ageing gut in the genesis of malnutrition in the elderly. We assess the burden of malnutrition in the elderly, exploring the role of comorbid conditions and neurohumoral changes that take place to contribute towards the process of anorexia associated with ageing. Following this, the review assesses physiological changes that occur in e...

Loss of chromosome 1p/19q in oligodendrogliomas represents a powerful predictor of good prognosis. Expression of internexin (INA), a neuronal specific intermediate filament protein, has recently been proposed as a surrogate marker for 1p/19q deletion based on the high degree of correlation between both parameters in oligodendrogliomas. The aim of this study was to assess further the diagnostic ...

Trends in Abortion Attitudes The GSS has carefully maintained the same wording and sequence of questions from year to year to avoid introducing context changes into the time series.* Respondents are asked whether a woman should be able to obtain a legal abortion for a series of reasons, beginning with “if there is a strong chance of defect in the baby” and ending with “if the woman wants it for...

Tooth root formation is initiated by the elongation of Hertwig’s epithelial root sheath (HERS). HERS cells are widely accepted to control root formation, but the mechanisms regulating HERS growth have not been elucidated. To solve this problem, we have established a new culture method for postnatal mouse mandibular molars and, using it, examined the role of insulin-like growth factor-I (IGF-I) ...

Editorial Franciscanum 177

Long-term potentiation (LTP) of synaptic strength at Schaffer collateral synapses has largely been attributed to changes in the number and biophysical properties of AMPA receptors (AMPARs). Small-conductance Ca21-activated K1 channels (SK2 channels) are functionally coupled with NMDA receptors (NMDARs) in CA1 spines such that their activity modulates the shape of excitatory postsynaptic potenti...

objective(s): in this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. materials and methods: lu-177 of 2.6-3 gbq/mg specific activity was obtained by irradiation of natural lu2o3 sample with thermal neutron flux of 4 × 1013 n.cm-2.s-1. the product was converted into chloride form which was further used for labeling of 177lu-phytate complex and che...

The objective of having a process operate with a capability index of 1.5 to 2.0 is a reasonable and economic objective. However, the arguments commonly used to explain the economics of this objective can only be described as statistical snake oil—a blend of tortured computations and incompatible, highly questionable assumptions, having a hypnotic effect and often resulting in a suspension of cr...