Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...

The antifungal activity of ethanol extract of Silybum marianum was investigated invitro against three strains of Rhizoctonia solani at different concentrations (5, 10, 15 and 20%). Bioassay of extract was conducted by poisoned food technique with three replications. The findings showed that strain of R. solani (Eggplant) was susceptible to concentrations of S. marianum more than other strains i...

Silymarin, an extract of the seeds of Silybum marianum L. (milk thistle), is used for treatment of liver diseases. It contains several active flavonolignans; the major are silybin, which is a mixture of diastereomers A and B, and silychristin. Low bioavailability of silybin and silychristin is related to low water solubility of these compounds. In order to enhance the solubility, S. marianum dr...

H. Fallah Huseini*, B. Larijani, R. Heshmat, H. Fakhrzadeh, B. Radjabipour, T. Toliat and Mohsin Raza Department of Pharmacology, Institute of Medicinal Plants, ACECR Tehran, Iran Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Department of Physiology, School of Medical Sci...

Seeds of Silybum marianum which have been used to treat liver diseases have an active component called silymarin. Hairy root cultures of S. marianum could be able to produce silymarin. There is evidence that the use of elicitors has been an important strategy for improving the production of secondary metabolites. Elicitation is an interesting topic to investigate cell signaling pathway in secon...

Deve dikeni (Silybum marianum) tohumuna çözücü ile ekstraksiyon yöntemi uygulanarak %7,3 verimle silimarin tozu elde edilmiştir. Ekstrakte tozun %57,8 içerdiği bulunmuştur. Silimarin içeriği dikkate alınarak silybum marianum tohumunun %4,21 olarak Ekstrakt ve orjinal silimarin, Fourier dönüşümlü kızıl ötesi spektroskopisi (FTIR), Optik Mikroskop, X-ışını kırınımı (XRD) taramalı elektron mikrosk...

In this study, the process of separating and analyzing oils from some plant seeds such as Washingtonia tree Silybum marianum(kulgan) Soxhlat apparatus was used in extraction process, where performed using organic solvents (Hexane Petroleum ether). Then appreciation percentage oil these plants. It found that marianum contain a higher than tree. Then, active functional groups were identified (FT-...

belonging to the family Compositae which comprises about 1000 genera and 20000 species. S. marianum is common in Kashmir at an altitude of 1800—4000 m and is cultivated for ornaments in gardens. The plant is used in the treatment of hepatitis, cirrhosis, regeneration from liver diseases, and liver poisoning. A decoction of this plant is also used by the local physicians for the treatment of a v...