We investigate the discrimination capacity of a single neuron model including the integrate-and-fire (IF) model and the IF-FHN model [Neural Networks, 14 (2001) 955], both theoretically and numerically. Both magnitude and frequency discrimination tasks are considered. It is found that for the magnitude discrimination task, with a small fraction of coherent inputs, an IF model and an IF-FHN mode...

Femoral head necrosis (FHN) is a metabolic cartilage disease of rapidly growing broilers. The aim of the present study was to investigate the role of basic fibroblast growth factor (bFGF) in the apoptotic processes associated with FHN. Broilers were selected and categorized based on clinical examination in 3 groups: healthy, femoral head separation, or femoral head separation with growth plate ...

Femoral head necrosis (FHN) is a skeletal problem in broiler chickens, where the proximal femoral head cartilage shows susceptibility to separation from its growth plate. The selected birds with FHN showed higher body weights and reduced plasma cholesterol. The proteomic differences in the plasma of healthy and FHN-affected chickens were explored using matrix-assisted laser desorption ionizatio...

BACKGROUND The differentiation between high and low cortisol responders to stress is of interest in determining the risk factors which may, along with genetic vulnerability, influence alcohol intake. STUDY 1 METHODS Thirty-two healthy volunteers, family history positive to alcoholism (FHP, n = 16) and family history negative (FHN, n = 16) attended two laboratory sessions during which alcoh...

BACKGROUND Worldwide, femoral head necrosis (FHN), which is also known as avascular necrosis of the femoral head or osteonecrosis of the femoral head, affects millions of people. Excess alcohol intake and steroid use are two common associations with FHN, but their pathogenesis remains unknown. The aim of this study was to develop an in vitro model using human chondrocytes to study alcohol-induc...

This article focuses on the qualitative analysis of complex dynamics arising in a few mathematical models neuroscience context. We first discuss three-dimensional FitzHugh–Rinzel (FHR) model and then illustrate those class non-homogeneous FitzHugh–Nagumo (Nh-FHN) reaction-diffusion systems. FHR Nh-FHN can be used to generate relevant wave-propagation phenomena Such include canards, mixed-mode o...

A cotton rat model of experimental human parainfluenza virus type 3 (PIV-3) infection was used to examine the efficacy of FHN, a novel chimeric glycoprotein which contains the extracellular regions of the fusion (F) and haemagglutinin-neuraminidase (HN) glycoproteins of PIV-3. The FHN protein was expressed in insect cells using a baculovirus vector system. FHN vaccination resulted in induction ...

We show that firing activity (spiking) can be regularized by noise in a FitzHugh-Nagumo (FHN) neuron model when operating slightly beyond the supercritical Hopf bifurcation (in the "canard" region). We also provide the conditions for imperfect phase locking between interspike intervals and low amplitude quasiharmonic oscillations. For the imperfect phase locking no need exists of an external si...

BACKGROUND Adolescents with a family history of alcoholism (FHP) are at risk for developing an alcohol use disorder (AUD), and some studies indicate that FHP individuals show deficits in executive functioning. The ability to make adaptive decisions is one aspect of successful executive functioning that is often measured during risk-taking tasks; however, this behavior has not been examined in F...

BACKGROUND AND PURPOSE Previous studies of patients who have undergone total hip arthroplasty (THA) due to femoral head necrosis (FHN) have shown an increased risk of revision compared to cases with primary osteoarthritis (POA), but recent studies have suggested that this procedure is not associated with poor outcome. We compared the risk of revision after operation with THA due to FHN or POA i...