Computer he most important recorded information medium on the Internet, and in the world at large, is the document. Although text might seem prosaic in contrast to multimedia objects, it is still the major medium for communicating information. Internet document retrieval can draw upon years of research results and practical experience in on-line information access as well as from traditional ph...

al contours of American social inequality have been transformed by the rapid growth in the prison and jail population.1 America’s prisons and jails have produced a new social group, a group of social outcasts who are joined by the shared experience of incarceration, crime, poverty, racial minority, and low education. As an outcast group, the men and women in our penal institutions have little a...

Degradation of certain inhibitor of apoptosis proteins (IAPs) appears to be critical in the initiation of apoptosis, but the factors that regulate their degradation in mammalian cells are unknown. Nrdp1/FLRF is a RING finger-containing ubiquitin ligase that catalyzes degradation of the EGF receptor family member, ErbB3. We show here that Nrdp1 associates with BRUCE/apollon, a 530 kDa membrane-a...

These are notes on Perelman’s papers “The Entropy Formula for the Ricci Flow and its Geometric Applications” [51] and “Ricci Flow with Surgery on Three-Manifolds’ [52]. In these two remarkable preprints, which were posted on the ArXiv in 2002 and 2003, Grisha Perelman announced a proof of the Poincaré Conjecture, and more generally Thurston’s Geometrization Conjecture, using the Ricci flow appr...

McGrath, R., Preda, V., Clifton-Bligh, P., Robinson, B., Sywak, M., Delbridge, L., Ward, P., Clifton-Bligh, R., Learoyd, D. (2016). Is there a role for an ultrasensitive thyroglobulin assay in patients with serum antithyroglobulin antibodies? A large (Australian) cohort study in differentiated thyroid cancer. Clinical Endocrinology, 84(2), 271-277. ...

We have generated a mouse line with a mutant allele of the mouse Bruce/Birc6 gene induced by gene trap mutagenesis. Based on its structural features, Bruce is a member of the family of apoptosis inhibitor proteins (IAPs). This mutation leads to a truncated transcript and protein and results in a complete loss of the wildtype Bruce protein. Bruce mutant mice die from a progressive loss of their ...