objective(s) studies have described immunomedulatory effects of sun exposure and ultraviolet radiation on infectious and neoplastic diseases. here the effect of exposure to low potency radiation of sun on the course of leishmaniasis in mice was studied. materials and methods fifteen balb/c mice were exposed to suberythemogenic doses of sun (mean 180 mj/cm2/day of uvb) 2 months before and 4 mont...

background and objectives: brucellosis is an important health problem in developing countries and no vaccine is available for the prevention of infection in humans. because of clinically infectious diseases and their economic consequences in human and animals, designing a proper vaccine against brucella is desirable. in this study, we evaluated the immune responses induced by a designed recombi...

conclusions results indicated that the present vaccination program is insufficient for immunity against measles in this area. the general population immunity was lower than the necessary level for the elimination of measles. therefore, sero-epidemiological studies are necessary to organize national programs for control and elimination of measles. results overall, 821 (91.2%) of the studied popu...

background: galantamine is a drug used for the treatment of alzheimer’s disease and some other cognitive disorders. it is an inhibitor of acetylcholinesterase however, interaction with nicotinic acetylcholine receptors has also been reported. owing to the significant role of cholinergic anti-inflammatory pathways in neuro-immunomodulation, we decided to examine the effect of galantamine on tula...

it is estimated that one third of the world's population is latently infected with tuberculosis (tb). the hiv epidemic fuels the tb epidemic by increasing the risk of reactivation of latent tb infection and by facilitating a more rapid progression of tb disease. although the incidence of tb is constant or decreasing in many regions of the world, rates remain high in developing countries as a co...

tetanus can be only prevented by vaccination because immunity against this disease is rarely acquired, even by natural infections. to maintain long-term protective immunity against tetanus, booster immunization is essential for adolescents and adults. most hospitalized cases and virtually all deaths occur in people over 60 years of age. the purpose of this study was to investigate the degree of...

neopterin, apyrazinopyrimidine compound, is produced by macrophages after induction by interferon gamma (ifn-y) and serves as a marker of cellular immune system activation followed by oxidative stress. the aim of this study was to determine urinary neopterin to creatinine ratio (uncr) as a surrogate marker of cell-mediated immune activation in multiple sclerosis (ms). three weekly early morning...

garlic and onions as dietary constituents and medicines have been used for many disorders which dates back to the early civilization. it has been shown that different species of allium have immunomodulating effects. in this study, we sought to determine if methanolic and chloroformic extracts of allim fistulosum l. (leek) have any effect on cell-mediated immune response in mice. methanolic and ...