The cyclic nature of walking can lead to repetitive stress and associated complications due to the rate of loading (ROL) experienced by the body at the initial contact of the foot with the ground. An individual's gait kinematics at initial contact has been suggested to give rise to the ROL, and a repetitive, high ROL may lead to several disorders, including osteoarthritis. Additionally, proprio...

This Application Note demonstrates the separation of eight tocopherol and tocotrienol compounds by supercritical fl uid chromatography (SFC) using the Agilent 1260 Infi nity Analytical SFC system. Calibration curves were generated for all compounds, and a real-life virgin olive oil sample was analyzed. The limits of detection and quantifi cation (LOD and LOQ) were determined as well as relative...

Dermal elastic fibres are extracellular matrix protein complexes produced by fibroblasts and involved in skin elasticity. Elastin fibres decrease with age as a result of reduced synthesis and increased degradation, resulting in skin sagging and reduced skin elasticity. In this study, we show that retinol (ROL), known to enhance dermal collagen production, is also enhancing elastin fibre formati...

Chemopreventive activities of all-trans retinoic acid (AtRA), 9-cis retinoic acid (9cRA), retinol (ROL) and b-carotene (bC) were evaluated during hepatocarcinogenesis. Rats received 1 mg/100 g body wt AtRA (AtRA group), 9cRA (9cRA group), ROL (ROL group), 7 mg/100 g body wt bC (bC group) or corn oil (CO group, controls). Hepatocyte nodule incidence was reduced (P 5 0.05) in bC group (46%), but ...

Introduction of the rol genes of Shigella dysenteriae 1 and Escherichia coli K-12 into Shigella flexneri carrier strains expressing the heterologous S. dysenteriae type 1 lipopolysaccharide resulted in the formation of longer chains of S. dysenteriae 1 O antigen. In bacteria producing both homologous and heterologous O antigen, this resulted in a reduction of the masking of heterologous O antig...

all-frans-Retinoic acid (RA) is used as a differentiation therapy for acute promyelocytic leukemia. Patients can become resistant to RA, and this resistance is thought to be mediated in part by an increase in the rate of RA metabolism. We have characterized the metabolism of all-frans-retinol (ROL; vitamin A) in NB4 cells, which are human promy elocytic leukemia cells. NB4 cells metabolize ROL ...

We have developed a yeast Pichia pastoris system for the high-level expression of recombinant Rhizopus oryzae lipase (ROL), which is a potentially effective catalyst in the solvent-free production of biodiesel fuel. In the glycerol fed-batch phase, the combination of the dissolvedoxygen-stat and gradient-control glycerol feeding strategies resulted in a higher cell biomass in the P. pastoris cu...

We investigated the capacity of Royal College of Surgeons (RCS) rat retinal pigment epithelial (RPE) cells to take up all-trans-retinol (ROL) (vitamin A) and to metabolize it into retinyl esters (RE). Cultures of RPE cells were established from RCS and control newborn rats. All-trans-ROL was delivered to the apical surface of the RPE monolayer. Retinoids were analyzed by high-performance liquid...

The differences in rhizosphere nitrification activities between high- and low- fertility soils appear to be related to differences in dissolved oxygen concentrations in the soil, implying a relationship to differences in the radial oxygen loss (ROL) of rice roots in these soils. A miniaturised Clark-type oxygen microelectrode system was used to determine rice root ROL and the rhizosphere oxygen...

In die Suid-Afrikaanse situasie is die verpleegkundige 'n kernfiguur in die lewering van primêre gesondheidsorgdienste. In die voorsiening van ’n veilige omgewing het sy ’n sekondêre rol in behoefteidentifisering en voorligting en dieselfde geld vir die aspek van toereikende voeding. Haar rol in basiese voorkomende gesondheidsorg en die sorg van bejaardes, gestremdes en chroniese siekes word re...