background cyclophosphamide (cp) is one of the most popular alkylating anticancer drugs despite its toxic side effects, including nephrotoxicity, hematotoxicity, mutagenicity, and immunotoxicity. capparis spinosa is a multipurpose plant that contains a number of chemically active and diverse secondary metabolites, particularly flavonoids. rutin and quercetin are two major flavonoids in the cape...

BACKGROUND/AIM To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an Alzheimer disease mice model. MATERIALS AND METHODS Thirty BALB/c mice divided into 5 groups (control, D-galactose, D-galactose + C. spinosa 50, D-galactose + C. spinosa 100,...

In this study, the effect of water and alcoholic (ethanol) extracts Caper Bush Capparis spinosa L., Cumine Cuminum cyminum L. , Black pepper Piper nigrum Sage Salvia sp. Cat thyme Teucrium polium plants on 4th instar larvae Culex quinquefasciatus have been evaluated .The results showed that extract P. had highest larvae, with 48h LC50 155. 9 ppm followed by ethanol C. 308.2 ,315.1and 791.4 resp...

The 'ethnodrug' Capparis spinosa L. has several pharmacological activities. First, it was found in previous experiments that an ethyl acetate extract of Capparis spinosa L. (CSE) exhibited antioxidant activity. In order to further research this finding, the present study investigate the blood biochemical indices, injury, energy metabolism, oxidative damage and mitochondrial membrane potential (...