Abstract Introduction Obstructive sleep apnea (OSA), which is associated with a high mortality, heterogeneous disease that affected by various pathophysiology. Although the severity of OSA divided based on apnea-hypopnea index (AHI), AHI alone did not sufficiently represent these pathologies. The objective this study to categorize using PSG data and compare characteristics each group including ...

Voltage-gated Ca(2+) channels (Ca(V)) are ubiquitously expressed in various cell types and play vital roles in regulation of cellular functions including proliferation. However, the molecular identities and function of Ca(V) remained unexplored in preadipocytes. Therefore, whole cell voltage-clamp technique, conventional/quantitative real-time RT-PCR, Western blot, small interfering RNA (siRNA)...

We report results from an ASCA X-ray study of DEM L316, an emission nebula in the Large Magellanic Cloud (LMC) consisting of two closely-spaced supernova remnants (SNRs). The SIS image shows separate X-ray sources located at the positions of the two radioand optically-emitting SNR shells, 0547−69.7A and 0547−69.7B (hereafter, shell A and B). The individual X-ray spectrum of each shell is well d...

AIM Using mice deficient in the CaV 3.1 T-type Ca(2+) channel, the aim of the present study was to elucidate the molecular identity of non-L-type channels involved in vascular tone regulation in mesenteric arteries and arterioles. METHODS We used immunofluorescence microscopy to localize CaV 3.1 channels, patch clamp electrophysiology to test the effects of a putative T-type channel blocker N...

Laetiporus sulphureus is an edible wood-rotting basidiomycete, growing on decaying logs, stumps, and trunks of many deciduous and coniferous tree species. This fungus produces relatively large striking yellowish or orange-coloured bracket-like fruitbodies. L. sulphureus is widely consumed as a nutritional food because of its fragrance and texture. In this study, two L. sulphureus strains, MFLUC...

The cation channel of sperm (CatSper) comprises four transmembrane subunits specifically expressed in human, equine, murine and ovine spermatozoa, apparently implicated in capacitation, hyperactivation and acrosome exocytosis. Western blotting and immunocytochemistry showed hereby that CatSper subunits are also present in boar spermatozoa, primarily over the sperm neck, tail and cytoplasmic dro...

The work described in this paper was carried out with the support of the BONE project (“Building the Future Optical Network in Europe”); a Network of Excellence funded by the European Commission through the 7th ICT-Framework Program. This research has been partially supported by the project CALM TEC2010-21405-C02-02 (subprogram TCM) funded by the Spanish Ministerio de Innovación y Ciencia and a...