We propose a new online learning algorithm which provably approximates maximum margin classifiers with bias, where the margin is defined in terms of p-norm distance. Although learning of linear classifiers with bias can be reduced to learning of those without bias, the known reduction might lose the margin and slow down the convergence of online learning algorithms. Our algorithm, unlike previo...

Objectives: To determine the predictive risk factors for isolated locoregional recurrence (LRR) in breast cancer patients with postmastectomy adjuvant therapy. Patients and Methods: The impacts of patients’ characteristics, tumor stage, and surgery on LRR were evaluated in patients with breast cancer having postmastectomy adjuvant therapy, according to their risk factors using univariate analys...

BACKGROUND To compare the surgical margin status after open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) performed in patients with T1a renal cell carcinoma (RCC). METHODS This was a propensity score-matched study including 702 patients with cT1a RCC treated with partial nephrectomy (PN) between May 2003 and July 2015. Perioperative parameters, including surgical margin wid...

BACKGROUND Surgical margin is an important prognostic factor in hepatectomy for patients with hepatocellular carcinoma (HCC). But the extent of surgical margins is still controversial. Our study was designed to systematically evaluate the prognosis of different width of resection margin. METHODS We conducted comprehensive searches of electronic databases including PubMed, MEDLINE, EMBASE, Coc...

This study was designed to define possible preoperative predictors of positive surgical margin after laparoscopic radical prostatectomy. We retrospectively analyzed the records of 296 patients with prostate cancer diagnosed by prostate biopsy, and eventually treated with laparoscopic radical prostatectomy. The prognostic impact of age, prostate volume, preoperative prostate-specific antigen, bi...

BACKGROUND Positive surgical margins are an adverse prognostic factor in patients undergoing prostatectomy for prostate cancer. The extent of margin positivity varies and its influence on clinical outcome is uncertain. AIMS To evaluate the linear extent of margin positivity and the number and location of positive sites as prognostic indicators in a series of prostatectomy specimens evaluated ...

PURPOSE While curative resection is the only chance of cure in pancreatic cancer, controversies exist about the impact of surgical margin status on survival. Non-standardized pathologic report and different criteria on the R1 status made it difficult to implicate adjuvant therapy after resection based on the margin status. We evaluated the influence of resection margins on survival by meta-anal...

BACKGROUND This study aimed investigate the effect of the level of invasion into fibromuscular band (FMB) of prostate on the positive surgical margin (PSM) and biochemical recurrence (BCR) after radical prostatectomy (RP) in patients with organ-confined (pT2) prostate cancer. METHODS The clinical and pathological data of 461 consecutive patients with pT2 prostate cancer were evaluated regardi...

OBJECTIVE To evaluate preoperative predictors of positive surgical margins and their location in Korean men undergoing radical prostatectomy. METHODS A total of 3227 patients who had undergone radical prostatectomy (open, robotic or laparoscopic) for clinically localized prostate cancer at three centers between 2000 and 2010 were analyzed. Patients were stratified by using the D'Amico risk cr...

The aim of the study was to examine the relationship between incisal condition after loop electrosurgical excision procedure (LEEP) operation for cervical intraepithelial neoplasia (CIN) patients and prognosis. A study of high-risk incisal margin positive cases was also performed. We compared the differences in the prognosis of the 1-year follow-up visit in the 120 CIN patients admitted to the ...