over the last five decades the association between coeliac disease and other autoimmune disorders such as autoimmune thyroid disease or diabetes mellitus type 1 has been well established through many studies and to this day is subject to on-going clinical and scientific investigation worldwide. while no link has been established between coeliac disease and type 2 diabetes mellitus, coeliac dise...

objective(s): leptin exerts various effects on appetite and body weight. disruption of the obesitygene is precedent to fatness. insulin or glucose elevates leptin, but streptozotocin reduces it. however, controversial data exist for the effects of leptin on diabetes and leptin level in each gender. leptin can damage the kidney function but little evidence exists for its hepatic effects. the aim...

background: nephrotic syndrome and type 1 diabetes mellitus are two common chronic conditions in children. co-existence of these conditions is an extremely rare finding. case presentation: this report presents a 6-year-old boy who was diagnosed with nephrotic syndrome five years ago and type 1 diabetes mellitus in infancy. renal biopsy showed membranous glomerulonephritis, which is a rare histo...

patients with type 1 diabetes mellitus have a high prevalence of coeliac disease, symptoms of which are often mild, atypical, or absent. untreated coeliac disease is associated with an increased risk of malignancy, particularly of lymphoma. therefore, we report a 9-year-old girl with coeliac disease, diabetes type 1 and selective iga deficiency. a 9-year-old female patient presented in august 2...

conclusions finally, based on the results obtained in this study, it can be concluded that the awareness of mothers of t1dm children has a good impact on blood sugar control, whereas the ses of families has no direct effect on blood sugar control. additionally, ses can indirectly impact on the consciousness of mothers and lead to the reduction of hba1c. results mothers’ mean knowledge score was...

type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (atd).genetic susceptibility for autoantibody formation in association with atd and type 1 diabetes mellitus has been described with varying frequencies, but there is still debate about its prevailing situation in iran.  we have therefore investigated the prevalence of anti-thyroid peroxidase (anti-tpo) and anti t...

conclusions these findings suggest that apelin does not play any significant role in regulating the pain threshold in type 1 diabetes mellitus during exercise training. results plasma apelin level was higher (0.3 vs. 0.1, p < 0.0001) and the tail-flick latency was lower (2.2 vs. 3.8, p < 0.0001) in the d group than in the nd group. after the training program, plasma apelin levels decreased in t...

background: the aim of the present clinical trial was to investigate the efficacy of autologous bone marrow mesenchymal stem cells (bm-mscs) in glycemic control of diabetic patients without using any immunosuppressive drugs over a nine-month period. method: twenty-three patients with t1dm, at 5 to 30 years of age and in both sexes, participated in this study. this trial consisted of two phases;...