[This corrects the article DOI: 10.1186/s40064-015-1177-2.].

In the present study, we showed that activation of human CD4 T cells can be induced by antiCD3 and collagen in a serum-free system . This activation was inhibited by the addition ofpeptides containing the RGD or Gly-Pro-X sequences . Significantly, we demonstrated that both the 1177 (CD26) structure and the VLA integrin family, particularly the VLA3 complex, contribute to the functional interac...

The Italian drill "DEEDRI" is going to be the lander based sample acquisition system for the Mars Surveyor Program of the Mars Sample Return mission. DEEDRI is capable to collect core/sand sample of the martian soil down to 50 era in depth. The MA_MISS experiment belongs to the DEEDRI system and it will be dedicated to observe the wall of the excavated hole in terms of infrared spectral reflect...

A radio holographic approach, developed by Pavelyev (1998), Hocke et al. (1999), Igarashi et al. (2000), is applied to observation of wave phenomena in the upper atmosphere using Global Positioning System "Microlab-l" satellite (GPS/MET) radio occultation data. In the current state the radio holography approach uses the radar focused synthetic aperture principle to obtain high spatial resolutio...

OBJECTIVE To analyse if platelet responsiveness to aspirin (ASA) may be associated with a different ability of platelets to generate nitric oxide (NO). PATIENTS/METHODS Platelets were obtained from 50 patients with stable coronary ischemia and were divided into ASA-sensitive (n = 26) and ASA-resistant (n = 24) using a platelet functionality test (PFA-100). RESULTS ASA-sensitive platelets te...

Endothelial nitric-oxide synthase (eNOS) is an important component of vascular homeostasis. During vascular disease, endothelial cells are exposed to excess reactive oxygen species that can alter cellular phenotype by inducing various signaling pathways. In the current study, we examined the implications of H(2)O(2)-induced signaling for eNOS phosphorylation status and activity in porcine aorti...

Qing Li 1,* , Xia Ji 1 and Steven Y. Liang 1,2 1 College of Mechanical Engineering, Donghua University, Shanghai 201620, China; [email protected] 2 George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0405, USA; [email protected] * Correspondence: [email protected] or [email protected]; Tel.: +86-021-6779-2583; Fax: +86-021-6779...

[This corrects the article on p. 1177 in vol. 7, PMID: 27570518.].

OBJECTIVE To find out whether dexamethasone induces an uncoupling of the endothelial nitric oxide synthase (eNOS). METHODS & RESULTS A major cause of eNOS uncoupling is a deficiency of its cofactor tetrahydrobiopterin (BH4). Treatment of human EA.hy 926 endothelial cells with dexamethasone decreased mRNA and protein expression of both BH4-synthesizing enzymes: GTP cyclohydrolase I and dihydro...