Pyrrolo[1,4]benzodiazepines are tricyclic compounds that are considered "privileged structures" since they possess a wide range of biological activities. The first encounter with these molecules was the isolation of anthramycin from cultures of Streptomyces, followed by determination of the X-ray crystal structure of the molecule and a study of its interaction with DNA. This opened up an intens...

The pathophysiology of post-stroke fatigue is poorly understood although it is thought to be a consequence of central nervous system pathophysiology. In this study we investigate the relationship between corticomotor excitability and self-reported nonexercise related fatigue in chronic stroke population. Seventy first-time non-depressed stroke survivors (60.36 12.4 years, 20 females, 56.81 63 m...

Positive solutions and eigenvalue intervals for nonlinear systems JIFENG CHU1,2, DONAL O’REGAN3 and MEIRONG ZHANG1 1Department of Mathematical Sciences, Tsinghua University, Beijing 100 084, China 2Department of Applied Mathematics, Hohai University, Nanjing 210 098, China 3Department of Mathematics, National University of Ireland, Galway, Ireland E-mail: [email protected]; [email protected]...

likely than nonusers to engage in risky sexual behavior and that they are less likely than nonusers to rely on condoms. In some studies, condom use has been treated as one component of a sexual-risk index, which is then related to substance use. In other research, condom use has been treated as a separate independent variable, which is then related to substance use directly. In this article, we...