OBJECTIVE To investigate commonalities in the clinical presentation of melancholia over time. METHOD I conducted a comparative study to 2 epidemiologically complete databases from 1875-1924 and 1995-2005. RESULTS Patients in the historical period (1875-1924, compared with 1995-2005) with a diagnosis of melancholia show a classic profile of endogenous onset, with remission after 6 months, ne...

OBJECTIVE To assess the differences in the pattern of mortality by sex, age and cause of death between 1875-1879 and 1970 for the Netherlands, and the contribution of different causes of death to the decrease of total mortality between these periods. METHODS Mortality data for 1875-1879 were extracted from one of the first publications after the start of the national cause-of-death register, ...