We present the case of a 71-year-old woman diagnosed with diffuse large B-cell non-Hodgkin lymphoma, stage IV-B, IPI 3, in complete remission after 6 cycles of rituximab-CHOP. Fivemonths after completing treatment the patient went to the Emergency Department for a picture of headache and diplopy of one month of evolution. During admission she present lumbosciatalgia refractory to pharmacologic ...

Introduction: Spinal tuberculosis is a serious health care problem and diagnosis is often difficult because many diseases may have similar imaging findings. Hence the need to describe findings of spinal tuberculosis with 2-[fluorine 18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) when compared to CT. Materials and Methods: Sixteen consecutive patients who underwent 18F-FDG ...

Positron emission tomography (PET) using the radiolabeled glucose analogue 18F-FDG allows uncovering glycolysis processes within cancer cells and reveals high value in diagnosis, staging, relapse and therapeutic response evaluation in several malignancies. Breast cancer presents considerable variability when it comes to 18F-FDG uptake, which results in different sensitivity and specificity valu...

In combined PET/CT imaging, functional data provided by 18FFDG increase diagnostic accuracy over conventional PET and CT in a variety of malignancies. The question to be raised is: how much is CT needed in PET/CT imaging? Discussion: In stand-alone CT imaging, contrast agents are applied to aid differentiation of anatomic structures, improve lesion localization, and support lesion characterizat...

CT) is a noninvasive radionuclide-based whole body imaging technique which combines both a Positron Emission Tomography (PET) scanner and an x-ray Computed Tomography (CT) scanner in a single gantry system. In PET, functional images are obtained which denotes spatial distribution of metabolic or biochemical activity in the body. These images are aligned with anatomical images obtained by CT sca...

To the Editor: Solitary splenic non-Hodgkin’s lymphoma (SSNHL) is a rare primary neoplasm; with an incidence less than 1% [1-3]. Authors have stated that solitary splenic lymphoma shows diffuse red pulp infiltration and enlargement without mass formation [1]. It cannot be pointed out by plain computed tomography (CT) or magnetic resonance imaging (MRI), ultrasounography (US) or Gallium-67 citra...

Choriocarcinoma (CC) is the highest malignant gestational trophoblastic tumor which causes high mortality without timely treatment. HIF-1α is a very important molecule promoting neoplasm aggressiveness, metastasis through the induction of the epithelial to mesenchymal transition (EMT). Several researches have shown that Notch signaling is necessary for coupling hypoxia to the EMT. However, the ...

The purpose of the study was to assess physiologic endometrial 18F-FDG uptake during the 4 phases of the menstrual cycle and to differentiate between physiologic and malignant endometrial uptake. Methods: Endometrial 18F-FDG uptake, expressed as standardized uptake value (SUV), was measured on PET/CT images of 285 consecutive female patients, of whom 246 (112 premenopausal and 134 postmenopausa...

A 35-y-old woman with pyrexia of unknown origin was referred to the Nuclear Medicine Department for an 18FFDG PET scan. She had undergone heart–lung transplantation for secondary pulmonary hypertension 4 mo previously. After transplantation she developed organizing pneumonia proven on transbronchial biopsies for which she required treatment with pulsed methyl prednisolone. Three months after su...